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CharacteristicsDetails
Definition
  • All studies included patients who had induced cardioinhibitory carotid sinus syndrome, with asystole of more than 3 seconds, in response to CSM.
    • about half the patients in the Brignole study36 had a mixed response
Details about CSM
  • In 2 studies36,115, patients had CSM conducted both supine and erect
  • 1 study simply reported that the patients had CSM47
Selection of patients
  • 1 study115 recruited patients from a cohort that had non- accidental falls and were attending the ED, and had not necessarily had TLoC (this may indicate an indirect population).
  • 1 study36 selected patients with carotid sinus syndrome, whose symptoms were judged to involve risk of major trauma or death, or interfered with their daily activity (because of frequency or intensity); the patients had either a cardioinhibitory response or a mixed response on CSM (about 50% of each)
Previous episodes of TLoC
  • The mean number of previous TLoC episodes across studies was around 2–4

From: 6, Diagnostic tests to direct pacing therapy

Cover of Transient Loss of Consciousness (‘Blackouts’) Management in Adults and Young People
Transient Loss of Consciousness (‘Blackouts’) Management in Adults and Young People [Internet].
NICE Clinical Guidelines, No. 109.
National Clinical Guideline Centre for Acute and Chronic Conditions (UK).
Copyright © National Clinical Guideline Centre for Acute and Chronic Conditions, 2010.

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