Psychiatric liaison vs. standard care

Quality assessmentSummary of findings
No of patientsEffectQuality
No of studiesDesignLimitationsInconsistencyIndirectnessImprecisionOther considerationsPsychiatric consultation-liasioncontrolRelative (95% CI)Absolute
Mortality
1randomised trialno serious limitationsno serious inconsistencyno serious indirectnessserious1,2none22/33119/338RR 1.18 (0.65 to 2.14)10 more per 1000 (from 20 fewer to 64 more)⊕⊕⊕○
MODERATE
Depression outcome 1. Diagnosis (at follow up)
1randomised trialno serious limitationsno serious inconsistencyno serious indirectnessserious1,2none245/331245/338RR 1.02 (0.93 to 1.12)14 more per 1000 (from 51 fewer to 87 more)⊕⊕⊕○
MODERATE
Physical health outcome/ QoL: 1. General physical wellbeing/ functioning (SF-12 physical etc) (Better indicated by less)
1randomised trialno serious limitationsno serious inconsistencyno serious indirectnessserious1,2none213237-SMD -0.06 (-0.25 to 0.12)⊕⊕⊕○
MODERATE
Treatment acceptability - leaving the study early for any reason
1randomised trialno serious limitationsno serious inconsistencyno serious indirectnessserious1,2none57/33140/338RR 1.46 (1 to 2.12)54 more per 1000 (from 0 more to 132 more)⊕⊕⊕○
MODERATE
1

Sparse data

2

Compatible with benefit and no benefit

From: Appendix 21, GRADE evidence profiles

Cover of Depression in Adults with a Chronic Physical Health Problem
Depression in Adults with a Chronic Physical Health Problem: Treatment and Management.
NICE Clinical Guidelines, No. 91.
National Collaborating Centre for Mental Health (UK).
Leicester (UK): British Psychological Society; 2010.
Copyright © 2010, The British Psychological Society & The Royal College of Psychiatrists.

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