Clinical settingPatients with malignant cytology. Samples identified from the records of a single pathology department
Participants and Country51 patients. USA
Study designRetrospective case series.
Target conditionIdentification of the primary tumour organ of origin. Reference standard not reported.
TestsIHC markers: CK7 and CK20
Follow upNot reported
Proportion with adenocarcinomaNot reported (all were described as carcinoma)
Primary or metastatic tumour?Metastatic
Sample typeCell blocks prepared from fine needle aspirates or malignant effusions

From: Guideline chapter 2, Diagnosis

Cover of Diagnosis and Management of Metastatic Malignant Disease of Unknown Primary Origin
Diagnosis and Management of Metastatic Malignant Disease of Unknown Primary Origin.
NICE Clinical Guidelines, No. 104.
National Collaborating Centre for Cancer (UK).
Copyright © 2010, National Collaborating Centre for Cancer.

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