Table 6.2Diagnostic yield of upper GI endoscopy

StudyPopulationEndoscopy detailsProportion of patients who had upper GI endoscopyProportion of adenocarcinoma histology in patients receiving endoscopyDiagnostic yield (%)
Katagiri 1999Bone metastases of unknown origin. It was not reported whether patients had GI symptoms, but it was probable as only selected patients had endoscopy.OGD24/64 (38%)Not reported4/24 (17%)
Kirsten 1987Metastases of unknown primary. It was not reported whether patients had GI symptoms, but it was probable as only selected patients had endoscopy.Gastroscopy21/286 (7%)Not reported0/21 (0%)
Schapira 1995Metastases of unknown primary. It was not reported whether patients had GI symptoms, but it was probable as only selected patients had endoscopy.Gastroscopy2/56 (4%)Not reported1/2 (50%)
Yamada 1975Metastases of unknown primary. It was not reported whether patients had GI symptoms,Gastroscopy18/18 (100%)100%6/18 (30%)

Abbreviations: OGD, oesophagogastroduodenoscopy.

From: Guideline chapter 2, Diagnosis

Cover of Diagnosis and Management of Metastatic Malignant Disease of Unknown Primary Origin
Diagnosis and Management of Metastatic Malignant Disease of Unknown Primary Origin.
NICE Clinical Guidelines, No. 104.
National Collaborating Centre for Cancer (UK).
Copyright © 2010, National Collaborating Centre for Cancer.

No part of this publication may be reproduced, stored or transmitted in any form or by any means, without the prior written permission of the publisher or, in the case of reprographic reproduction, in accordance with the terms of licenses issued by the Copyright Licensing Agency in the UK. Enquiries concerning reproduction outside the terms stated here should be sent to the publisher at the UK address printed on this page.

The use of registered names, trademarks etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant laws and regulations and therefore for general use.

PubMed Health. A service of the National Library of Medicine, National Institutes of Health.