Examples of variation in labeled and delivered doses of inhaled asthma controller medications

Brand Name/Product (Generic Name)Labeled Dose (mcg)“Ex-Valve” Dose (mcg)“Ex-Actuator Dose” (Delivered Dose, mcg)
Advair Diskus® DPI (fluticasone/salmeterol)100/50100/5093/45
250/50250/50233/45
500/50500/50465/45
Alvesco® (ciclesonide)8010080
160200160
Flovent Diskus® (fluticasone)505046
10010094
250250229
Flovent® HFA (fluticasone)445044
110125110
220250220
Foradil Aerolizer® DPI (formoterol)121210
Pulmicort Flexhaler® (budesonide)180180160
909080
QVAR® HFA (beclomethasone)405040
8010080
Serevent Diskus® (salmeterol)505047
Serevent® Inhalation Aerosol (salmeterol)212521
Symbicort Turbuhaler® (budesonide/formoterol) *Available in Canada*100/6100/680/4.5
200/6200/6160/4.5
Symbicort® (budesonide/formoterol)80/4.591/5.180/4.5
160/4.5181/5.1160/4.5

From: Appendix D, Labeled and delivered doses

Cover of Drug Class Review: Controller Medications for Asthma
Drug Class Review: Controller Medications for Asthma: Final Update 1 Report [Internet].
Jonas DE, Wines RCM, DelMonte M, et al.
Portland (OR): Oregon Health & Science University; 2011 Apr.
Copyright © 2011 by Oregon Health & Science University.

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