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Table 24Endocrine adverse events among dementia patients – atypical antipsychotics compared with placebo

PlaceboIntervention Groups
Adverse EventsDrug# of Studies# Adverse EventsSample Size# Adverse EventsSample SizePooled OR95% CINNH
DiabetesRisperidone1523842350.810.16, 3.80NC
ProlactinRisperidone102380235NCNCNC

CI = confidence interval; NC = not calculated; NNH = number needed to harm; OR = odds ratio

From: Results

Cover of Off-Label Use of Atypical Antipsychotics: An Update
Off-Label Use of Atypical Antipsychotics: An Update [Internet].
Comparative Effectiveness Reviews, No. 43.
Maglione M, Maher AR, Hu J, et al.

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