Table 5.11.4ESS in randomized controlled trials of mandibular advancement devices vs. mandibular advancement devices

Study
PMID
Baseline AHI (SD) [eligibility]Baseline ESS (SD)Duration (design)InterventionsNo. AnalyzedBaseline (SD)Change (final)Net diff or Diff95% CIP BtwDropout, %Study Quality
Campbell 2009219
18989715
25 (7) [10–40]11.6 (4.7)6 wk (PL)MAD objective *1211.0(5.3)−1.52.3−1.4, 6.0 nd6B
MAD subjective 1611.6(4.7)−3.8
Vanderveken 2008221
17673699
13 (11) [<40]8 (5)4mo (XO)MAD cm §237(5)−20−1.6, 1.6 **nd8B
MAD tp ††237(5)−2
Walker Engstrom 2003220
14569523
50 (4) [≥20]11.5 (3.1)6 mo(PL)50% MAD ‡‡3711.7(3.1)−3.10.9−0.4, 2.2nd8B
75% MAD §§4011.5(3.1)−4
*

objective adjustment at 3 weeks following PSG-based feedback

Estimated from reported data

self-adjustment of mandibular advancement device during the entire study duration (6 weeks)

§

Custom made mandibular advancement device

**

Estimated from reported data

††

Pre- molded thermoplastic mandibular advancement device

‡‡

50% mandibular advancement (mean mandibular advancement 5.0 mm)

§§

75% of mandibular advancement (mean mandibular advancement 7.2 mm)

objective adjustment at 3 weeks following PSG-based feedback

Estimated from reported data

self-adjustment of mandibular advancement device during the entire study duration (6 weeks)

Custom made mandibular advancement device

Estimated from reported data

Pre- molded thermoplastic mandibular advancement device

50% mandibular advancement (mean mandibular advancement 5.0 mm)

75% of mandibular advancement (mean mandibular advancement 7.2 mm)

From: Appendix D, Summary Tables

Cover of Diagnosis and Treatment of Obstructive Sleep Apnea in Adults
Diagnosis and Treatment of Obstructive Sleep Apnea in Adults [Internet].
Comparative Effectiveness Reviews, No. 32.
Balk EM, Moorthy D, Obadan NO, et al.

PubMed Health. A service of the National Library of Medicine, National Institutes of Health.