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Table 5.5.4Quality of life and functional outcomes in randomized controlled trials of bilevel CPAP vs. CPAP

Study
PMID
Baseline AHI (SD)Baseline ESS (SD)Duration (design)InterventionsNo. AnalyzedOutcome measureFavorsIf significant differenceDropout, %Study Quality
Net difference95% CITest RangeP Btw
“Worst”“Best”
Piper 2008197
18203817
nd14.5 (IQR = 12–19)3 mo (PL)Bilevel CPAP18SF-3600B
CPAP18Mental
SF-360
Physical
Piper 2008197
18203817
nd14.5 (IQR12–19)3 mo (PL)Bilevel CPAP18mean of slowest 10% reactionBilevel CPAPnet diff of median 0.650.030B
CPAP18
Lapses0
Median (ms)0
Gay 2003195
14655921
44 (24)121 mo (PL)Bilevel CPAP12FOSQ00C
CPAP15
Khayat 2008196
18641111
32 (16)12.6 (6.3)3 mo (PL)Bilevel CPAP13MLHFQ04C
CPAP11

From: Appendix D, Summary Tables

Cover of Diagnosis and Treatment of Obstructive Sleep Apnea in Adults
Diagnosis and Treatment of Obstructive Sleep Apnea in Adults [Internet].
Comparative Effectiveness Reviews, No. 32.
Balk EM, Moorthy D, Obadan NO, et al.

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