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Table 5.2.10Quality of life in randomized controlled trials of CPAP vs. sham control

Study
PMID
Baseline AHI (SD)Baseline ESS (SD)Duration (design)InterventionsNo. AnalyzedOutcomeFavors *If Significant DifferenceDropout, %Study Quality
Net Diff95 CITest RangeP Btw
“Worst”“Best”
Smith 2007166
17470670
36 (23) [≥15]10 (5)6 wk (XO)AutoCPAP23SF-360NS12A
Sham23PCS
SF-360NS
MCS
Siccolli 2008165
1e9014075
nd15.2 (4.0)4 wk (PL)CPAP50SF-36CPAP8.20.4, 16.0 01000.013B
Sham CPAP49PCS
SF-36CPAP10.82.8, 18.8 01000.002
MCS
Calgary SAQLI total scoreCPAP0.90.4, 1.4 §070.001
Egea 2008147
17904420
35 (17) [>10]7.3 (4.5)3 mo (PL)CPAP20SF-360NS18B
Sham CPAP25PCS
SF-360NS
MCS
Barbe 2001142
11388814
57 (15) [≥30]7.0 (2)6 wk (PL)CPAP29SF-360NS2B
Sham CPAP25PCS
SF-360
MCS
Montserrat 2001162
11520724
54 (19) [>10]16.9 (5.6)6 wk (PL)CPAP23SF-360NS6B
Sham CPAP22PCS
SF-360NS
MCS
Marshall 2005159
15860720
22 (nd) [nd]12.5 (4.3)3 wk (XO)CPAP29SF-360NS6B
Sham CPAP29PCS
SF-360NS
MCS
*

The noted intervention statistically significantly favors the patient (net better score on test). 0 = no difference.

Estimated from reported data.

Estimated from reported data.

§

Estimated from reported data.

The noted intervention statistically significantly favors the patient (net better score on test). 0 = no difference.

Estimated from reported data.

Estimated from reported data.

Estimated from reported data.

From: Appendix D, Summary Tables

Cover of Diagnosis and Treatment of Obstructive Sleep Apnea in Adults
Diagnosis and Treatment of Obstructive Sleep Apnea in Adults [Internet].
Comparative Effectiveness Reviews, No. 32.
Balk EM, Moorthy D, Obadan NO, et al.

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