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Table 15-18Imipramine compared to desmopressin and oxybutynin - Clinical summary of findings

OutcomeImipramineDesmopressin and oxybutyninRelative risk (95% CI)Absolute effectQuality
Number of children who had 0–1 wet nights per month3/23 (13%)14/22 (63.6%)RR 0.2 (0.07 to 0.62)509 fewer per 1000 (from 242 fewer to 591 fewer)LOW
Mean number of wet nights per week at the end of treatment2322-MD 1.07 (0.06 to 2.08)VERY LOW

From: 15, Tricyclic medication and the management of bedwetting

Cover of Nocturnal Enuresis
Nocturnal Enuresis: The Management of Bedwetting in Children and Young People.
NICE Clinical Guidelines, No. 111.
National Clinical Guideline Centre (UK).
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