Table 1.7-6Intranasal desmopressin compared to intranasal desmopressin and amitriptyline - Clinical study characteristics

OutcomeNumber of studiesDesignLimitationsInconsistencyIndirectnessImprecision
Number of children who achieved 14 consecutive dry nights1randomised trialno serious limitationsno serious inconsistencyno serious indirectnessserious1
Mean number of wet nights per week at end of treatment1randomised trialno serious limitationsno serious inconsistencyno serious indirectnessserious1
Mean number of wet nights per week at end of follow up1randomised trialno serious limitationsno serious inconsistencyno serious indirectnessserious1
Number of children who dropped out by end of trial1randomised trialno serious limitationsno serious inconsistencyno serious indirectnessserious1
1

The confidence interval crosses the MID(s)

The confidence interval crosses the MID(s)

From: Appendix H, GRADE profile tables

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