Table 1.5-44Enuresis alarm compared to enuresis alarm with desmopressin for children with monosymptomatic nocturnal enuresis - Clinical study characteristics

OutcomeNumber of studiesDesignLimitationsInconsistencyIndirectnessImprecision
Number of children who achieved at least 75% reduction in the number of wet nights1randomised trialvery serious1no serious inconsistencyno serious indirectnessserious2
Mean number of wet nights per week at the end of treatment1randomised trialvery serious2no serious inconsistencyno serious indirectnessserious2
Number of children who dropped out by the end of the trial1randomised trialvery serious1no serious inconsistencyno serious indirectnessserious2
1

The study had unclear allocation concealment and blinding

2

The confidence interval crosses the MID(s)

The study had unclear allocation concealment and blinding

The confidence interval crosses the MID(s)

From: Appendix H, GRADE profile tables

Cover of Nocturnal Enuresis
Nocturnal Enuresis: The Management of Bedwetting in Children and Young People.
NICE Clinical Guidelines, No. 111.
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