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Table 1.5-13Dry bed training with an alarm with parents as therapist compared to an alarm - Clinical study characteristics

OutcomeNumber of studiesDesignLimitationsInconsistencyIndirectnessImprecision
Number of children who achieved 14 consecutive dry nights1randomised trialvery serious1no serious inconsistencyno serious indirectnessserious2
Mean number of wet nights per week at the end of treatment (no sd)1randomised trialvery serious1,3no serious inconsistencyno serious indirectnessserious4
Number of children who relapsed1randomised trialvery serious1no serious inconsistencyno serious indirectnessserious2
1

Bollard 1981 had an unclear blinding method and unclear allocation concealment

2

The confidence interval crosses the MID(s)

3

Results from Cochrane review - paper did not present this result

4

No information on variability was given in the study, therefore calculation of standard deviation was not possible and the mean difference and CI were not estimable

Bollard 1981 had an unclear blinding method and unclear allocation concealment

The confidence interval crosses the MID(s)

Results from Cochrane review - paper did not present this result

No information on variability was given in the study, therefore calculation of standard deviation was not possible and the mean difference and CI were not estimable

From: Appendix H, GRADE profile tables

Cover of Nocturnal Enuresis
Nocturnal Enuresis: The Management of Bedwetting in Children and Young People.
NICE Clinical Guidelines, No. 111.
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