Table C-11KQ 3a: TPMT status to guide therapy, clinical outcomes – Risk of bias assessment of included study, part 1

StudyWas the method of randomization appropriate?Adequacy of allocation concealment?Were Investigators and participants blinded to interventions?Was there blinded assessment of outcomes?Were groups similar at baseline?Were outcomes described adequately?Was there intention-to-treat analysis?Was there a potential for financial conflict of interest?
Newman, 201045YesUnclearNoYes for mortality and SAE, no for WDAE and other intermediate outcomesYesYesYesNo

From: Appendix C, Evidence Tables

Cover of Assessment of Thiopurine Methyltransferase Activity in Patients Prescribed Azathioprine or Other Thiopurine-Based Drugs
Assessment of Thiopurine Methyltransferase Activity in Patients Prescribed Azathioprine or Other Thiopurine-Based Drugs.
Evidence Reports/Technology Assessments, No. 196.
Booth RA, Ansari MT, Tricco AC, et al.

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