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Table 11Relative risks of CVD events from high intensity compared to low intensity statin treatment from meta-analysis of IDEAL (Pedersen, T. R., Faergeman, O., Kastelein, J. J. et al, 2005) & TNT (LaRosa, J. C., Grundy, S. M., Waters, D. D. et al, 2005) for patients with stable coronary artery disease

OutcomeMean (RR)Lower CLUpper CLStandard error
MI0.810.720.910.0597
Stroke0.820.700.960.0806
Transient Ischemic Attack0.790.650.940.0941
Peripheral Artery Disease0.870.691.110.1213
Heart Failure0.770.650.920.0886
Revascularisation0.780.710.860.0489
Unstable Angina0.840.691.010.0972
Cardiovascular death0.920.721.170.1239
Death from other causes1.001.001.00

From: Appendix C, Health Economic Modelling

Cover of Lipid Modification
Lipid Modification: Cardiovascular Risk Assessment and the Modification of Blood Lipids for the Primary and Secondary Prevention of Cardiovascular Disease [Internet].
NICE Clinical Guidelines, No. 67.
National Collaborating Centre for Primary Care (UK).
Copyright © 2008, Royal College of General Practitioners.

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