Table 73Summary of evidence profile for lithium monotherapy in long-term maintenance of bipolar II disorder

LithiumValproate semisodium
Evidence for efficacy (quality)Data are inconclusive (low) for efficacy outcomesData are inconclusive (low) for efficacy outcomes
Evidence for acceptability/tolerability (including switching) (quality)Data are inconclusive (low) for acceptability/tolerability outcomesData are inconclusive (low) for acceptability/tolerability outcomes

From: 9, THE MEDICAL AND PHARMACOLOGICAL MANAGEMENT OF BIPOLAR DISORDER – PART II

Cover of Bipolar Disorder
Bipolar Disorder: The Management of Bipolar Disorder in Adults, Children and Adolescents, in Primary and Secondary Care.
NICE Clinical Guidelines, No. 38.
National Collaborating Centre for Mental Health (UK).
Leicester (UK): British Psychological Society; 2006.
Copyright © 2006, The British Psychological Society & The Royal College of Psychiatrists.

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