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Table 4Summary evidence table for trials of stand-alone brief interventions for people who misuse drugs

Brief intervention versus control for stimulants or opioidsBrief intervention versus control for cannabisIndividual relapse- prevention CBT versus brief interventionGroup relapse- prevention CBT versus brief intervention
Total no. of trials (total no. of participants)3 RCTs
(N = 1,268)
4 RCTs (1 cluster randomised)
(N = 764)
3 RCTs
(N = 602)
1 RCT
(N = 205)
Study IDBAKER2005
BERNSTEIN2005
MARSDEN2006
COPELAND2001
MCCAMBRIDGE 2004*
STEPHENS2000
STEPHENS2002
BAKER2005
COPELAND2001
STEPHENS2002
STEPHENS2000
Evidence profile table number (Appendix 16)Table A16-1Table A16-1Table A16-1Table A16-1
Overall quality of evidenceHighModerateModerateLow
Point abstinenceStimulants 6-month follow-up: RR 1.30 (1.09 to 1.55), K = 3, N = 1,268
Heroin follow-up: RR 1.54 (1.09 to 2.16), K = 1, N = 1,175
Heroin and cocaine follow-up: RR = 1.45 (1.02 to 2.05), K = 1, N = 1,175
Continuous duration for cannabis: 3–4 months: RR 3.33 (1.99 to 5.56), K = 3, N = 613
Proportion days not using cannabis: 3-month follow-up: SMD −0.42 (−0.81 to −0.03), K = 1, N = 105
Continuous duration of abstinence for cannabis: 8–12 months: RR = 2.41 (−1.01 to 5.73), K = 2, N = 345
Cannabis follow-up: RR 2.60 (1.45 to 4.66) K = 2, N = 462
Follow-up: SMD 0.24 (−0.13 to 0.51), K = 1, N = 102
Amphetamine: RR 0.89 (0.57 to 1.39), K = 1, N = 140
Drug useCannabis 3-month follow-up (adjusted for baseline differences): B = 11.54 (6.91 to 16.18), p <0.0001, K = 1, N = 200Cannabis 4-month follow-up: SMD −0.68 (−0.88 to −0.49), K = 2, N = 432Cannabis 9-month follow-up: SMD −0.43 (−0.58 to −0.17), K = 1, N = 245Cannabis 12-month follow-up: SMD 0.03 (−0.65 to 0.23), K = 1, N = 179

RR >1 favours intervention; in comparisons of CBT and brief interventions RR >1 favours CBT; negative SMD values favour intervention; in comparisons of CBT and brief interventions negative SMD values favour CBT; B >1 favours intervention.

*

Adjusted for clustering effects.

Adjusted for clustering effects.

From: 7, BRIEF INTERVENTIONS AND REDUCTION OF INJECTION AND SEXUAL RISK BEHAVIOURS

Cover of Drug Misuse
Drug Misuse: Psychosocial Interventions.
NICE Clinical Guidelines, No. 51.
National Collaborating Centre for Mental Health (UK).
Leicester (UK): British Psychological Society; 2008.
Copyright © 2008, The British Psychological Society & The Royal College of Psychiatrists.

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