Case management

Quality assessment
No of studiesDesignLimitationsConsistencyDirectnessOther considerations
Initiation into treatment (Mejta 1997, Morgenstern 2005, Needels 2005: Study 1, Needels 2005: Study 2)
4Randomised trialsNo limitationsImportant inconsistency (−1)2Some uncertainty (−1)1None
Retention at follow up (Jansson 2005, Needels 2005: Study1, Needels 2005: Study2, Sorensen 2005)
4Randomised trialsNo limitationsNo important inconsistencySome uncertainty (−1)1None
Abstinence from Cocaine (endpoint) (Jansson 2005, Needels 2005: Study 1, Needels 2005: Study 2)
3Randomised trialsNo limitationsImportant inconsistency (−1)2Some uncertainty (−1)1None
Abstinence from opiates (Jansson 2005, Sorensen 2005)
2Randomised trialsNo limitationsNo important inconsistencySome uncertainty (−1)1Imprecise or sparse data (−1)3
Abstinence from cannabis (Needels 2005: Study 1, Needels 2005: Study 2)
2Randomised trialsNo limitationsNo important inconsistencySome uncertainty (−1)1None
Summary of findings
OutcomeNo of patientsEffectQuality
Case managementControlRelative (95% CI)Absolute (95% CI)
Initiation into treatment471/1025 (46%)345/1003 (34.4%)RR 1.34 (1.04 to 1.72)-[plus sign in circle][plus sign in circle]○○
Low
Retention at follow up139/758 (18.3%)134/772 (17.4%)RR 1.20 (0.84 to 1.74)-[plus sign in circle][plus sign in circle][plus sign in circle]
Moderate
Abstinence from Cocaine (endpoint)144/726 (19.8%)143/740 (19.3%)RR 1.09 (0.79 to 1.49)-[plus sign in circle][plus sign in circle]○○
Low
Abstinence from opiates28/54 (51.9%)39/66 (59.1%)RR 0.88 (0.63 to 1.23)-[plus sign in circle][plus sign in circle]○○
Low
Abstinence from cannabis117/704 (16.6%)110/706 (15.6%)RR 1.06 (0.85 to 1.33)-[plus sign in circle][plus sign in circle][plus sign in circle]
Moderate
1

No UK studies

2

I-squared > 50%

3

CIs compatible with benefit and no benefit

No UK studies

I-squared > 50%

CIs compatible with benefit and no benefit

From: APPENDIX 16, EVIDENCE PROFILE TABLES

Cover of Drug Misuse
Drug Misuse: Psychosocial Interventions.
NICE Clinical Guidelines, No. 51.
National Collaborating Centre for Mental Health (UK).
Leicester (UK): British Psychological Society; 2008.
Copyright © 2008, The British Psychological Society & The Royal College of Psychiatrists.

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