Table 8Baseline input parameters from different health states (annual transition probabilities)

Age3050657585
From FH no prior CVD event to
MI0.3160.0220.0050.0040.005
Stroke0.0030.0050.0110.0110.013
peripheral artery disease0.0020.0020.0040.0070.017
heart failure0.0040.0020.0010.0030.004
revascularisations0.1330.0090.0030.0010.000
 unstable angina0.1890.0120.0020.0020.002
cardiovascular death0.1620.0150.0050.0050.005
From MI to
 MI0.0220.0220.0270.0390.039
 Stroke0.0070.0080.0120.0230.023
 heart failure0.0120.0120.0120.0120.012
revascularisations0.0670.0670.0670.0670.067
 unstable angina0.0210.0210.0210.0210.021
cardiovascular death0.0050.0070.0150.0300.030
From Stroke to
Stroke0.0770.1670.2070.2630.333
MI0.0020.1670.0060.0080.010
heart failure0.0050.0050.0050.0050.005
revascularisations0.0000.0000.0000.0000.000
 unstable angina0.0060.0060.0060.0060.006
 cardiovascular death0.0050.0110.0260.0590.122
From peripheral artery disease to
 MI0.0160.0160.0160.0160.016
Stroke0.0160.0160.0160.0160.016
 cardiovascular death0.0820.0820.0820.0820.082
From Heart failure to
 heart failure0.0420.0420.0420.0420.042
 MI0.0080.0080.0080.0080.008
Stroke0.0020.0020.0020.0020.002
revascularisations0.0000.0000.0000.0000.000
unstable angina0.0080.0080.0080.0080.008
cardiovascular death0.0450.0450.0450.0450.045
From revascularisations to
revascularisations0.0390.0390.0390.0390.039
MI0.0300.0300.0300.0300.030
Stroke0.0100.0100.0100.0100.010
 heart failure0.0150.0150.0150.0150.015
cardiovascular death0.0060.0060.0060.0060.006
Unstable angina to
revascularisations0.1420.1420.1420.1420.142
MI0.0490.0490.0490.0490.049
Stroke0.0140.0140.0140.0140.014
 heart failure0.0440.0440.0440.0440.044
cardiovascular death0.0050.0050.0050.0050.005

From: Appendix E, Health Economic modelling

Cover of Identification and Management of Familial Hypercholesterolaemia (FH)
Identification and Management of Familial Hypercholesterolaemia (FH) [Internet].
NICE Clinical Guidelines, No. 71.
National Collaborating Centre for Primary Care (UK).
Copyright © 2008, Royal College of General Practitioners.

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