Comparison: CBT + medical treatment versus medical treatment

OutcomeMeta-analysis detailsSummary Statisticsp (hetero) and I2Comments:Study qualityDirectnessImprecisionInconsistencyReporting BiasGRADE CommentsGRADE Evidence Rating
Global symptoms - change in overall wellbeing1 trials; 24 patients; from meta-analysisMD=−1.88 (95%CI −2.33, − 1.43)Statistically significant, favours CBT + medical treatment; scale 1 to 7 (high=worse)GoodIndirect setting- - minor, secondarysparse data----Not applicableSmall study (n=24) but precise data; no pyschiatric comorbidities; secondary care.Low
Quality of life1 trials; 24 patients; from meta-analysisMD=21.73 (95%CI 9.04, 34.42)Scale max 144; stat sig; favours CBT+medical treatmentGoodIndirect setting- - minor, secondarysparse dataconsistent---GI QoL instrument; no psychiatric comorbidities; secondary care. Small RCTLow

From: Appendix F, Grading the evidence

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