Comparison: mebeverine MR vs mebeverine conventional

OutcomeMeta-analysis detailsSummary Statisticsp (hetero) and I2Comments:Study qualityDirectnessImprecisionInconsistencyReporting BiasGRADE CommentsGRADE Evidence Rating
Global improvement of IBS symptoms (no. patients)2 trials; 208 patients; from meta analysis; (parallel design);RR=1.03 (95%CI 0.88, 1.2)p=0.28; I2 =0.153%no significant difference between typesGoodDirectPreciseconsistent---I of the 2 studies took place in primary care. 1/2 studies was not blinded and duration < 4w. Overall downgraded to moderate.Moderate

From: Appendix F, Grading the evidence

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