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10.8.5Is it cost effective to screen pregnant women for rubella immunity?

StudyRef.PopulationInterventionOutcomesResultsCommentsStudy typeEL
Stray-Pederson, 1982619Model based on annual pregnant population of 50,000 in Norway and prognosis of congenital rubella in unvaccinated population (n = 38 during epidemic period; n = 6 during nonepidemic period)Modelling to assess cost benefit of rubella vaccination programmes (with goal of preventing rubella in pregnant women and subsequent congenital rubella syndrome)Comparison of various vaccination programmesAll strategies were cost effective
Based on cost/benefit ratios, net benefit came from vaccination offered to all women in puberty, supplemented with offering vaccination to nonimmunised women after delivery and women at high risk of exposure
If participation in vaccination programme < 100%, vaccination offered at two ages (e.g. childhood and puberty) gives best results in prevention of congenital cases
EE3 (?)

From: Evidence tables

Cover of Antenatal Care
Antenatal Care: Routine Care for the Healthy Pregnant Woman.
NICE Clinical Guidelines, No. 62.
National Collaborating Centre for Women's and Children's Health (UK).
London: RCOG Press; 2008 Mar.
Copyright © 2008, National Collaborating Centre for Women’s and Children’s Health.

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