Table 11.15Characteristics of included studies on diagnostic value of maternal history of previous SPTB

Study and ELStudy characteristicsPopulation characteristicsSample size (% of study population)Timing of screening test with threshold (prevalence of test positive)Outcome in weeks (incidence of SPTB)Diagnostic value with 95% CI
Goldenberg (1998)880 (USA)
EL 1b
Prospective cohort, multicentre.Singleton pregnancies.
Exclusions: multiple gestations, cervical cerclage, placenta previa, major fetal anomaly.
(58.4% – rest were primiparas)
History of previous SPTB (20–37 weeks) at 22–24 weeks visit
(21.2% in study population)
< 32, < 35, and < 37 (11.9% at < 37)For SPTB < 37 weeks: ST 0.42 (0.35–0.49), SP 0.82 (0.80–0.83)
Iams (1998)881 (USA)
Prospective cohort, multicentre.Singleton pregnancies.
(secondary analysis of data from Goldenberg study to measure risk of recurrent SPTB – lower limit of gest. age for SPTB reduced from 20 to 18 weeks)
1282History of previous SPTB at 18–26, 27–31, and 32–36 weeks.< 35History of previous SPTB at 27–31 weeks: ST 0.33 (0.23–0.44), SP 0.88 (0.86–0.89)
History of previous SPTB at 32–36 weeks: ST 0.67 (0.56–0.77), SP 0.73 (0.70–0.76)
Kristensen (1995)882 (Denmark)
Retrospective cohort, multicentre.
(records from National Health Registers used
All women with permanent address in Denmark who gave birth to their first singleton infant in 1982 and a second in 1982–8713 967
History of previous SPTB at < 37 weeks
(3.5% in study population)
< 37
(2.2% – SPTB, 3.5% all PTD)
For SPTB < 37 weeks: ST 0.19 (0.14–0.23), SP 0.97 (0.96–0.97)

From: 11, Screening for clinical problems

Cover of Antenatal Care
Antenatal Care: Routine Care for the Healthy Pregnant Woman.
NICE Clinical Guidelines, No. 62.
National Collaborating Centre for Women's and Children's Health (UK).
London: RCOG Press; 2008 Mar.
Copyright © 2008, National Collaborating Centre for Women’s and Children’s Health.

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