Table 4.29CRP

StudyPatient groupUseResults – baseline predictors
1 case-control study74,75
Level III
Population at risk (no previous history of arthritis or other rheumatic disease)Risk of RA development (cases vs controls)NS: CRP
1 case-series83
Level Ib
PolyarthritisRA development vs no developmentNS: CRP
1 case-control study76
Level II
UA patientsRisk of RA development (cases vs controls)NS: CRP
1 case-series29
Level II
UA patientsPredictor of RA developmentSignificant: CRP (univariate median level 14 vs 8, p <0.001 and multivariate 5–50 mg/titer OR 1.6, 95% CI 0.9 to 3.0, p=0.13; >50 mg/titer OR 5.0, 95% CI 2.0 to 12.1, p=0.00)

From: 4, Referral, diagnosis and investigations

Cover of Rheumatoid Arthritis
Rheumatoid Arthritis: National Clinical Guideline for Management and Treatment in Adults.
NICE Clinical Guidelines, No. 79.
National Collaborating Centre for Chronic Conditions (UK).
Copyright © 2009, Royal College of Physicians of London.

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