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Chronic Kidney Disease: National Clinical Guideline for Early Identification and Management in Adults in Primary and Secondary Care

Chronic Kidney Disease: National Clinical Guideline for Early Identification and Management in Adults in Primary and Secondary Care

NICE Clinical Guidelines - National Collaborating Centre for Chronic Conditions (UK)

Version: September 2008

Blood pressure control

There is strong evidence that lowering blood pressure reduces cardiovascular risk and progression of CKD. The optimal treatment target remains poorly defined and considerable confusion has occurred because there is a lack of conformity between recommended treatment targets in different disease guidelines and in the Quality and Outcomes Framework. The objective of this section was both to consider the evidence and to rationalise treatment targets with those recommended by the NICE guidelines for management of type 2 diabetes and hypertension.

Evidence Tables

Un-separated Blood experiment: 10 volunteers each provided 7 blood samples (clotted). Samples were kept at RT exposed to light until centrifugation at 0.5 h, 4 h, 8 h, 16 h, 24 h, 36, and 48 h-post collection. All samples were assayed for creatinine with the kinetic Jaffe Roche method standardised against IDMS.

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