Table A17-18Detoxification plus individual drug counselling versus control

Quality assessment
No of studiesDesignLimitationsConsistencyDirectnessOther considerations
Completion of detoxification (Rawson 1983)
1Randomised trialsNo limitationsNo important inconsistencySome uncertainty (−1)1Imprecise or sparse data (−1)2
Abstinence: opiate-negative urinalysis or self-report (endpoint) (Rawson 1983)
1Randomised trialsSerious limitations (−1)3No important inconsistencySome uncertainty (−1)1Imprecise or sparse data (−1)2
Relapse: drug-dependent or incarcerated (6-month follow-up) (Rawson 1983)
1Randomised trialsNo limitationsNo important inconsistencySome uncertainty (−1)1Imprecise or sparse data (−1)2
Summary of findings
OutcomeNo of patientsEffectQuality
Individual drug counsellingControlRelative (95% CI)Absolute (95% CI)
Completion of detoxification4/25 (16%)3/25 (12%)RR 1.33 (0.33 to 5.36)-⊕⊕○○
Low
Abstinence: opiate- negative urinalysis or self-report (endpoint)15/25 (60%)13/25 (52%)RR 1.15 (0.70 to 1.89)-⊕○○○
Very low
Relapse: drug- dependent or incarcerated (6-month follow-up)7/25 (28%)12/25 (48%)RR 0.58 (0.28 to 1.23)-⊕⊕○○
Low
1

Old study

2

Single study

3

Given low completion rate, high proportion of abstinence unlikely

From: APPENDIX 17, EVIDENCE PROFILE TABLES

Cover of Drug Misuse
Drug Misuse: Opioid Detoxification.
NICE Clinical Guidelines, No. 52.
National Collaborating Centre for Mental Health (UK).
Leicester (UK): British Psychological Society; 2008.
Copyright © 2008, The British Psychological Society & The Royal College of Psychiatrists.

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