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MethodsParticipantsOutcomesInterventionsNotes
ZENG2005
n= 70
Age: Mean 34
Sex: 60 males 10 females

Diagnosis:
 100% opiate dependence by DSM-III-R

Exclusions: - <18 >50 years of age
- physical and psychiatric problems

 Baseline: Methadone + acupuncture/methadone
 Years of opiate use: 6.00(2.82)/6.23(2.93)

Data Used
 Withdrawal severity
 Completion
Notes: DROPOUTS: Methadone + acupuncture 4/35 methadone = 9/35

Group 1 N= 35
 Opiate agonist: methadone with inpatient - Received methadone once a day. Starting dose 1mg/kg then reduced daily by approx 20% until 1 mg on day 10 and zero dose on day 11
 Acupuncture with inpatient - Received acupuncture once a day. Needles were retained for 30 minutes, during which they were manipulated three times
Group 2 N= 35
 Opiate agonist: methadone with inpatient - Received methadone once a day. Starting dose 1mg/kg then reduced daily by approx 20% until 1 mg on day 10 and zero dose on day 11

Study quality 1+
Study Type: RCT (randomised controlled trial)

Blindness: No mention
Duration (days): Mean 10

Setting: China, Drug Rehabilitation Centre
Notes: RANDOMISATION: no mention of method used

From: APPENDIX 15, CHARACTERISTICS OF REVIEWED STUDIES

Cover of Drug Misuse
Drug Misuse: Opioid Detoxification.
NICE Clinical Guidelines, No. 52.
National Collaborating Centre for Mental Health (UK).
Leicester (UK): British Psychological Society; 2008.
Copyright © NCCMH.

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