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Urinary Tract Infection in Children: Diagnosis, Treatment and Long-term Management

Urinary Tract Infection in Children: Diagnosis, Treatment and Long-term Management

NICE Clinical Guidelines - National Collaborating Centre for Women's and Children's Health (UK)

Version: August 2007

Acute management

A variety of antibiotics are used in the UK to treat acute UTI in infants and children. The choice of antibiotic, route of administration and the duration of treatment depend upon on a combination of clinical presentation and local sensitivity patterns. The aim is to eradicate the infection, relieve symptoms and minimise the development of renal parenchymal defects. Oral antibiotics and shorter courses are generally more convenient for patients, have fewer risks and adverse effects and are less costly. In addition, appropriate use of antibiotics is likely to result in the development of less resistance to antibiotics in the community. This chapter aims to summarise the different considerations underlying the administration of antibiotics for the management of a first-time urinary tract infection and to develop the best possible advice on safe and effective treatment for infants and children based the points above.

Search strategies


Summary of recommendations, patient flow pathway and algorithm

Infants and children presenting with unexplained fever of 38 °C or higher should have a urine sample tested after 24 hours at the latest.

Excluded studies

Adult patients (mean age 50.5 years)

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