Table 7.44Study withdrawals

Withdrawals outcomeReferenceInterventionAssessment timeOutcome/effect size
Knee osteoarthritis
Number of withdrawals1 RCT (Deal et al. 1991) (N=70)Topical capsaicin vs placeboOver treatment periodN=1 2.9% (topical) and N=5 14.3% (placebo)
Hand
Number of study withdrawals1 RCT (Schnitzer et al. 1994) (N=59)Topical capsaicin vs placeboOver treatment periodN=4 13.8% (topical) and N=7 23.3% (placebo)
Mixed (knee, ankle, elbow, wrist, shoulder)
Number of study withdrawals1 RCT (Altman et al. 1994) (N=113)Topical capsaicin vs placeboOver treatment periodN=11 19.3% (topical) and N=6
10.7% (placebo)
Withdrawals due to AEs1 RCT (Altman et al. 1994) (N=113)Topical capsaicin vs placeboOver treatment periodN=5, 8.7% (topical) and N=0, 0% (placebo)
Withdrawals due to treatment failure1 RCT (Altman et al. 1994) (N=113)Topical capsaicin vs placeboOver treatment periodN=6 10.5% (topical) and N=4, 7.5% (placebo)
Mixed (knee, hip, shoulder, hand)
Number of withdrawals1 RCT (McCleane 2000) (N=200)Topical capsaicin vs placeboOver treatment periodBoth N=10 20%

From: 7, Pharmacological management of osteoarthritis

Cover of Osteoarthritis
Osteoarthritis: National Clinical Guideline for Care and Management in Adults.
NICE Clinical Guidelines, No. 59.
National Collaborating Centre for Chronic Conditions (UK).
Copyright © 2008, Royal College of Physicians of London.

All rights reserved. No part of this publication may be reproduced in any form (including photocopying or storing it in any medium by electronic means and whether or not transiently or incidentally to some other use of this publication) without the written permission of the copyright owner. Applications for the copyright owner’s written permission to reproduce any part of this publication should be addressed to the publisher.

PubMed Health. A service of the National Library of Medicine, National Institutes of Health.