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Table 6.86Rescue medication

Rescue medication outcomeReferenceInterventionAssessment timeOutcome/effect size
Knee
Glucosamine hydrochloride
Rescue paracetamol, No. of tablets taken1 RCT (Clegg et al. 2006) (N=1583)GH vs placebo24 weeks (end of treatment)NS
Glucosamine sulphate
Use of rescue analgesia, % completers not using rescue medication1 RCT (Herrero-Beaumont et al. 2007) (N=325)GS vs placeboover 6 months (end of study)22% and 9% respectively, p=0.027
Favours GS

From: 6, Non-pharmacological management of osteoarthritis

Cover of Osteoarthritis
Osteoarthritis: National Clinical Guideline for Care and Management in Adults.
NICE Clinical Guidelines, No. 59.
National Collaborating Centre for Chronic Conditions (UK).
Copyright © 2008, Royal College of Physicians of London.

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