5.2.5Assessing endometrial biopsy in treatment of luteal phase defect effect of treatment for luteal phase defect

StudyPopulationInterventionOutcomesResultsStudy typeEL
Karamardian et al. 19923541 RCT

3 comparative studies

19 case series studies
Progesterone versus no treatment

Progesterone, clomifene versus no treatment

Progesterone,, clomifene, FSH, bromocriptine etc
Risk of pregnancy

Pregnancy rates
Risk of pregnancy non- significant, RR 1.9 (CI 0.4 to

No significant benefit

Pregnancy rates: no significant benefit with large CIs
SRIb–3

From: Evidence tables

Cover of Fertility
Fertility: Assessment and Treatment for People with Fertility Problems.
NICE Clinical Guidelines, No. 11.
National Collaborating Centre for Women's and Children's Health (UK).
London (UK): RCOG Press; 2004 Feb.
Copyright © 2004, National Collaborating Centre for Women’s and Children’s Health.

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