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Drug Class Review: Newer Drugs for the Treatment of Diabetes Mellitus: Final Report [Internet]

Drug Class Review: Newer Drugs for the Treatment of Diabetes Mellitus: Final Report [Internet]

Drug Class Reviews - Oregon Health & Science University

Version: August 2008

Results

We identified 134 citations from our literature search (Figure 1). Six randomized controlled trials (with 1 companion paper) and 4 pooled analyses fulfilled inclusion criteria. No comparative cohort or case-control studies reporting long-term benefits or harms were identified. Details of included studies are found in Evidence Tables 1– and quality assessment in Evidence Table 4. Trials excluded upon review of the full text are listed in Appendix D. In the FDA Medical and Statistical Reviews, 6 relevant trials were identified, of which 4 were published and already included in our review. The remaining two trials could not be found in the published literature. No good quality systematic reviews of pramlintide were identified for inclusion.

Evidence Tables

Baseline characteristics of trials and studies of newer drugs for the treatment of diabetes mellitus

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