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A.D.A.M. Medical Encyclopedia [Internet]. Atlanta (GA): A.D.A.M.; 2013.

A.D.A.M. Medical Encyclopedia.

Luteinizing hormone (LH) blood test

ICSH - blood test; Luteinizing hormone - blood test; Interstitial cell stimulating hormone - blood test

Last reviewed: September 30, 2013.

The LH blood test measures the amount of luteinizing hormone (LH) in blood. LH is a hormone released by the pituitary gland, located on the underside of the brain.

How the test is performed

A blood sample is needed.

How to prepare for the test

Your health care provider will ask you to temporarily stop medicines that may affect the test results. Be sure to tell your provider about all the medicines you take. These include:

If you are a woman of childbearing age, the test may need to be done on a specific day of your menstrual cycle. Tell your provider if you have recently been exposed to radioisotopes, such as during a nuclear medicine test.

How the test will feel

When the needle is inserted to draw blood, some people feel moderate pain. Others feel only a prick or stinging sensation. Afterward, there may be some throbbing or a slight bruise. These soone go away.

Why the test is performed

In women, an increase in LH level at mid-cycle causes release of eggs (ovulation). Your doctor will order this test to see if:

  • You are ovulating, when you are having trouble getting pregnant or have periods that are not regular
  • You have reached menopause

If you are a man, the test may be ordered if you have signs of infertility or lowered sex drive. The test may be ordered if you have signs of a pituitary gland problem.

Normal Values

Normal result for an adult women are:

  • Before menopause: 5 to 25 IU/L
  • Level peaks even higher around the middle of the menstrual cycle
  • Level then becomes higher in women after menopause: 14.2- to 52.3 IU/L

LH levels are normally low during childhood.

Normal result for men over 18 years of age is around 1.8 to 8.6 IU/L.

IU/L stands for international unit per liter.

Normal value ranges may vary slightly among different laboratories. Some labs use different measurements or test different samples. Talk to your doctor about the meaning of your specific test result.

What abnormal results mean

In women, a higher than normal level of LH is seen:

In men, a higher than normal level of LH  may be due to:

In children, a higher than normal level is seen in early (precocious) puberty.

A lower than normal level of LH may be due to the pituitary gland not making enough hormone (hypopituitarism).

What the risks are

Veins and arteries vary in size from one patient to another and from one side of the body to the other. Obtaining a blood sample from some people may be more difficult than from others.

Other risks associated with having blood drawn are slight but may include:

  • Excessive bleeding
  • Fainting or feeling light-headed
  • Hematoma (blood accumulating under the skin)
  • Infection (a slight risk any time the skin is broken)

References

  1. Borawski D, Bluth MH. Reproductive function and pregnancy. In: McPherson RA, Pincus MR, eds. Henry's Clinical Diagnosis and Management by Laboratory Methods. 22nd ed. Philadelphia, Pa: Elsevier Saunders;  2011:chap 25.
  2. Melmed S, Kleinberg D, Ho K. Pituitary physiology and diagnostic evaluation. In: Melmed S, Polonsky KS, Larsen PR, Kronenberg HM, eds. Williams Textbook of Endocrinology. 12th ed. Philadelphia, Pa: Elsevier Saunders; 2011: chap 8.

Review Date: 9/30/2013.

Reviewed by: Susan Storck, MD, FACOG, Chief, Eastside Department of Obstetrics and Gynecology, Group Health Cooperative of Puget Sound, Bellevue, Washington; Clinical Teaching Faculty, Department of Obstetrics and Gynecology, University of Washington School of Medicine. Also reviewed by David Zieve, MD, MHA, Bethanne Black, and the A.D.A.M. Editorial team.

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What works?

  • What is the best timing technique for intrauterine inseminationWhat is the best timing technique for intrauterine insemination
    It remains unclear which technique of timing for intrauterine insemination results in the best treatment outcome, a live birth. Intrauterine insemination (IUI) is an assisted reproduction procedure that places sperm directly into the uterus. Timing of IUI can be performed with hormone (luteinising hormone) detection in urine or blood, human chorionic gonadotropin (hCG) injection and other more infrequently used methods. Results of this review of randomised controlled trials indicate there is no difference in live birth rates between timing methods, but the amount of evidence is scarce. The optimal moment for the actual insemination in relation to either luteinising hormone (LH) surge or hCG administration is also unclear.
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