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A.D.A.M. Medical Encyclopedia [Internet]. Atlanta (GA): A.D.A.M.; 2013.

A.D.A.M. Medical Encyclopedia.

Chronic

Last reviewed: January 21, 2013.

Chronic refers to something that continues over an extended period of time. A chronic condition is usually long-lasting and does not easily or quickly go away.

Chronic is the opposite of acute.

Review Date: 1/21/2013.

Reviewed by: Linda J. Vorvick, MD, Medical Director and Director of Didactic Curriculum, MEDEX Northwest Division of Physician Assistant Studies, Department of Family Medicine, UW Medicine, School of Medicine, University of Washington. Also reviewed by A.D.A.M. Health Solutions, Ebix, Inc., Editorial Team: David Zieve, MD, MHA, David R. Eltz, Stephanie Slon, and Nissi Wang.

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    Chronic hepatitis B virus (HBV) infection causes significant mortality, morbidity, and it is an economic burden worldwide. Although the current approved therapies show beneficial effects, response to treatment is not satisfactory, patients are at high risk of developing viral resistance, and serious adverse events occur. The objective of this review was to evaluate the benefits and harms of phyllanthus species compared with commonly used antiviral drugs for patients with chronic HBV infection. In a previous Cochrane Hepato‐Biliary Group systematic review we have compared phyllanthus species versus placebo or no intervention. In that review, we were unable to find convincing evidence to support the use of phyllanthus species for patients with chronic hepatitis B.
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  • Acute vs. chronic conditions.

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