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AHFS Consumer Medication Information [Internet]. Bethesda (MD): American Society of Health-System Pharmacists; 2000-2011.

AHFS Consumer Medication Information.

Neomycin Topical(nee oh mye' sin)

Last reviewed: August 1, 2010.

Why is this medication prescribed?

Neomycin, an antibiotic, is used to prevent or treat skin infections caused by bacteria. It is not effective against fungal or viral infections.

This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information.

How should this medicine be used?

Neomycin comes in cream and ointment that is applied to the skin. Neomycin usually is used one to three times a day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Use neomycin exactly as directed. Do not use more or less of it or use it more often than prescribed by your doctor.

Thoroughly clean the infected area, allow it to dry, and then gently rub the medication in until most of it disappears. Use just enough medication to cover the affected area. You should wash your hands after applying the medication.

Do not apply neomycin to a child's diaper area, especially if the skin is raw, unless directed to do so by a doctor. If you are directed to apply neomycin to a child's diaper area, do not use tightly fitting diapers or plastic pants. They can increase the absorption of the drug, which can cause harmful effects.

Apply only small amounts of neomycin to scrapes, cuts, burns, sores, and wounds, and do not apply it more frequently than directed. Neomycin can be absorbed into the body through broken skin and cause kidney problems and hearing difficulty.

What special precautions should I follow?

Before using neomycin,

  • tell your doctor and pharmacist if you are allergic to neomycin or any other drugs.

  • tell your doctor and pharmacist what prescription and nonprescription medications you are taking, including vitamins.

  • tell your doctor if you have or have ever had kidney disease.

  • tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while using neomycin, call your doctor.

What should I do if I forget a dose?

Apply the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not apply a double dose to make up for a missed one.

What side effects can this medication cause?

Neomycin may cause side effects. If you experience any of the following symptoms, call your doctor immediately:

  • irritation

  • burning

  • redness

  • rash

  • itching

  • hearing difficulty

  • decreased urination

If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online [at http://www.fda.gov/Safety/MedWatch] or by phone [1-800-332-1088].

What storage conditions are needed for this medicine?

Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom). Neomycin may become discolored, but this change does not affect its action. Throw away any medication that is outdated or no longer needed. Talk to your pharmacist about the proper disposal of your medication.

What other information should I know?

Keep all appointments with your doctor. Neomycin is for external use only. Do not let neomycin get into your eyes, nose, or mouth, and do not swallow it. Do not apply dressings, bandages, cosmetics, lotions, or other skin medications to the area being treated unless your doctor tells you.

Do not let anyone else use your medication. Ask your pharmacist any questions you have about refilling your prescription.

If you still have symptoms of infection after you finish the neomycin, call your doctor.

It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.

This report on medications is for your information only, and is not considered individual patient advice. Because of the changing nature of drug information, please consult your physician or pharmacist about specific clinical use.

The American Society of Health-System Pharmacists, Inc. represents that the information provided hereunder was formulated with a reasonable standard of care, and in conformity with professional standards in the field. The American Society of Health-System Pharmacists, Inc. makes no representations or warranties, express or implied, including, but not limited to, any implied warranty of merchantability and/or fitness for a particular purpose, with respect to such information and specifically disclaims all such warranties. Users are advised that decisions regarding drug therapy are complex medical decisions requiring the independent, informed decision of an appropriate health care professional, and the information is provided for informational purposes only. The entire monograph for a drug should be reviewed for a thorough understanding of the drug's actions, uses and side effects. The American Society of Health-System Pharmacists, Inc. does not endorse or recommend the use of any drug. The information is not a substitute for medical care.

AHFS® Consumer Medication Information. © Copyright, 2011. The American Society of Health-System Pharmacists, Inc., 7272 Wisconsin Avenue, Bethesda, Maryland. All Rights Reserved. Duplication for commercial use must be authorized by ASHP.

The following brand names are from RxNorm, a standardized nomenclature for clinical drugs produced by the National Library of Medicine:

Brand names

  • Myciguent

Brand names of combination products

  • Atopalm First Aid (containing Bacitracin, Neomycin, and Polymyxin B)

  • Campho-Phenique Maximum Strength (containing Bacitracin, Neomycin, and diperodon)

  • Cortisporin (containing Hydrocortisone, Neomycin, and Polymyxin B)

  • Cortisporin Ointment (containing Bacitracin, Hydrocortisone, Neomycin, and Polymyxin B)

  • Lanabiotic (containing Bacitracin, Neomycin, Polymyxin B, and pramoxine)

  • Medi-Quik (containing Bacitracin, Neomycin, and Polymyxin B)

  • Mycitracin Plus Pain Reliever (containing Bacitracin, Neomycin, Polymyxin B, and pramoxine)

  • Mycitracin Triple Antibiotic (containing Bacitracin, Neomycin, and Polymyxin B)

  • Neo-Cortef (containing Hydrocortisone and Neomycin)

  • Neo-Decadron Cream (containing Dexamethasone and Neomycin)

  • Neo-Medrol Acetate (containing Methylprednisolone and Neomycin)

  • Neosporin Ointment (containing Bacitracin, Neomycin, and Polymyxin B)

  • Neosporin Plus Maximum Strength (containing Bacitracin, Neomycin, Polymyxin B, and pramoxine)

  • Neosporin Plus Maximum Strength Cream (containing Neomycin, Polymyxin B, and pramoxine)

  • Neosporin Plus Maxium Strength Ointment (containing Bacitracin, Lidocaine, Neomycin, and Polymyxin B)

  • ProCoMycin (containing Bacitracin, Lidocaine, Neomycin, and Polymyxin B)

  • Septa (containing Bacitracin, Neomycin, and Polymyxin B)

  • Spectrocin Plus (containing Bacitracin, Neomycin, Polymyxin B, and pramoxine)

  • Tri Biozene (containing Bacitracin, Neomycin, Polymyxin B, and pramoxine)

  • Tribiotic Plus (containing Bacitracin, Neomycin, and Polymyxin B)

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