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Results: 1 to 20 of 815

Association of a difference in systolic blood pressure between arms with vascular disease and mortality: a systematic review and meta-analysis

Bibliographic details: Clark CE, Taylor RS, Shore AC, Ukoumunne OC, Campbell JL.  Association of a difference in systolic blood pressure between arms with vascular disease and mortality: a systematic review and meta-analysis. Lancet 2012 Available from: http://www.thelancet.com/journals/lancet/article/PIIS0140-6736%2811%2961710-8/abstract

Database of Abstracts of Reviews of Effects (DARE): Quality-assessed Reviews [Internet] - Centre for Reviews and Dissemination (UK).

Version: 2012

Antibiotics for vascular diseases: a meta-analysis of randomized controlled trials

This review evaluated the efficacy of antibiotics in the treatment of atherosclerotic vascular diseases. The authors concluded that antibiotic treatment does not significantly reduce the occurrence of new vascular events or death. Given the likely presence of publication bias and the poor reporting of review methods, the reliability of the authors' conclusions is weakened.

Database of Abstracts of Reviews of Effects (DARE): Quality-assessed Reviews [Internet] - Centre for Reviews and Dissemination (UK).

Version: 2005

Antiplatelet treatment for prevention of cerebrovascular events in patients with vascular diseases: a systematic review and meta-analysis

BACKGROUND AND PURPOSE: The efficacy and safety of different antiplatelet regimes for prevention of stroke in patients at high risk were investigated in a systematic review and meta-analysis.

Database of Abstracts of Reviews of Effects (DARE): Quality-assessed Reviews [Internet] - Centre for Reviews and Dissemination (UK).

Version: 2014

Telephone based self-management support by 'lay health workers' and 'peer support workers' to prevent and manage vascular diseases: a systematic review and meta-analysis

BACKGROUND: Improved prevention and management of vascular disease is a global priority. Non-health care professionals (such as, 'lay health workers' and 'peer support workers') are increasingly being used to offer telephone support alongside that offered by conventional services, to reach disadvantaged populations and to provide more efficient delivery of care. However, questions remain over the impact of such interventions, particularly on a wider range of vascular related conditions (such as, chronic kidney disease), and it is unclear how different types of telephone support impact on outcome. This study assessed the evidence on the effectiveness and cost-effectiveness of telephone self-management interventions led by 'lay health workers' and 'peer support workers' for patients with vascular disease and long-term conditions associated with vascular disease.

Database of Abstracts of Reviews of Effects (DARE): Quality-assessed Reviews [Internet] - Centre for Reviews and Dissemination (UK).

Version: 2013

Dipyridamole for preventing stroke and other vascular events in patients with vascular disease

Patients with symptoms of arterial disease have a high risk of getting a (possibly fatal) stroke or heart attack (myocardial infarction). Antiplatelet therapy with drugs like aspirin prevents blood clotting and reduces the risk of strokes, heart attacks, and death from vascular disease. Dipyridamole, another antiplatelet drug, given on its own or together with aspirin might reduce the risk even further. This review included 29 studies involving 23019 participants. When we compared the effects of dipyridamole (alone or together with aspirin) with aspirin alone there was no evidence of an effect on death from vascular causes. When we compared the effects on the occurrence of vascular events (strokes, heart attacks, and deaths from vascular diseases) the combination of aspirin and dipyridamole had an advantage over aspirin alone. This result holds particularly true for patients with ischaemic stroke.

Cochrane Database of Systematic Reviews: Plain Language Summaries [Internet] - John Wiley & Sons, Ltd.

Version: 2010

Impact of mind body therapies on vascular endothelial dysfunction and implications for cardiovacular disease management

Bibliographic details: Prasad K, Reriani MK, Murad MH, Sood A, Prasad A.  Impact of mind body therapies on vascular endothelial dysfunction and implications for cardiovacular disease management. Journal of Complementary and Integrative Medicine 2011; 8(1):26 Available from: http://www.bepress.com/jcim/vol8/iss1/26/

Database of Abstracts of Reviews of Effects (DARE): Quality-assessed Reviews [Internet] - Centre for Reviews and Dissemination (UK).

Version: 2011

Cryoplasty for peripheral vascular disease

The benefit of cryoplasty over conventional balloon angioplasty has yet to be definitely established as there are few randomised controlled trials evaluating this method. The technical success rates and rates of unobstructed arteries (primary patency) compared with conventional angioplasty seen in seven trials (478 patients) were inconsistent. Long‐term outcomes, in particular, are as yet to be assessed fully. Currently there are insufficient data to support the routine use of cryoplasty over conventional balloon angioplasty in the treatment of peripheral arterial disease.

Cochrane Database of Systematic Reviews: Plain Language Summaries [Internet] - John Wiley & Sons, Ltd.

Version: 2013

[Effectiveness of lumbar sympathectomy in the treatment of occlusive peripheral vascular disease in lower limbs: systematic review]

BACKGROUND AND OBJECTIVES: The aim of this work has been to check the scientific evidence on the efficacy of lumbar sympathectomy in the treatment of peripheral arterial disease of lower limbs.

Database of Abstracts of Reviews of Effects (DARE): Quality-assessed Reviews [Internet] - Centre for Reviews and Dissemination (UK).

Version: 2010

Gene therapy as a novel therapeutic option in the treatment of peripheral vascular disease: systematic review and meta-analysis

This review concluded that the available data suggested that gene therapy conferred no benefits in peak walking time, claudication onset time, nor ankle brachial pressure index for patients with peripheral vascular disease. The reliability of the conclusions is unclear given the incomplete reporting of the review methods and the small number of trials and participants reviewed.

Database of Abstracts of Reviews of Effects (DARE): Quality-assessed Reviews [Internet] - Centre for Reviews and Dissemination (UK).

Version: 2008

Effectiveness of mindfulness-based stress reduction and mindfulness based cognitive therapy in vascular disease: a systematic review and meta-analysis of randomised controlled trials

OBJECTIVE: To determine the effectiveness of mindfulness-based stress reduction (MBSR) and mindfulness-based cognitive therapy (MBCT) on psychological and physical outcomes for people with vascular disease.

Database of Abstracts of Reviews of Effects (DARE): Quality-assessed Reviews [Internet] - Centre for Reviews and Dissemination (UK).

Version: 2014

Intravascular brachytherapy for peripheral vascular disease

SCIENTIFIC BACKGROUND : Percutaneous transluminal angioplasties (PTA) through balloon dilatation with or without stenting, i.e. vessel expansion through balloons with or without of implantation of small tubes, called stents, are used in the treatment of peripheral artery occlusive disease (PAOD). The intravascular vessel irradiation, called intravascular brachytherapy, promises a reduction in the rate of repeated stenosis (rate of restenosis) after PTA.

Database of Abstracts of Reviews of Effects (DARE): Quality-assessed Reviews [Internet] - Centre for Reviews and Dissemination (UK).

Version: 2008

Aspirin in the primary and secondary prevention of vascular disease: collaborative meta-analysis of individual participant data from randomised trials

This review concluded that the use of aspirin for the prevention of cardiac events needed to be weighed against an increase in major bleeds. There was no justification in advocating the routine use of aspirin. Despite some concerns, the analyses contained a large number of people and the results seemed consistent. The conservative conclusions were likely to be reliable.

Database of Abstracts of Reviews of Effects (DARE): Quality-assessed Reviews [Internet] - Centre for Reviews and Dissemination (UK).

Version: 2009

There good evidence that statins given in late life to individuals at risk of vascular disease have no effect in preventing dementia

Evidence accumulating from biological and epidemiological studies suggest that high levels of serum cholesterol may promote the pathological processes that lead to Alzheimer's disease. Lowering cholesterol in experimental animal models slows the expression of Alzheimer's pathology. These findings raise the possibility that treating humans with cholesterol lowering medications might reduce the risk of developing Alzheimer's disease. The statin family of medications (lovastatin, pravastatin,simvastatin, and others) are powerful cholesterol lowering agents of proven benefit in vascular disease. Several clinical studies comparing the occurrence of Alzheimer's disease between users of statins and non‐users of statins suggest that risk of Alzheimer's disease is substantially reduced among the users. However, because these studies are not randomized trials, they provide insufficient evidence to recommend statin therapy. Two randomized trials have since been carried out and neither showed any reduction in occurrence of AD or dementia in patients treated with statins compared to those given placebo. Statins cannot therefore be recommended for the prevention of AD or dementia.

Cochrane Database of Systematic Reviews: Plain Language Summaries [Internet] - John Wiley & Sons, Ltd.

Version: 2009

The effects of lowering LDL cholesterol with statin therapy in people at low risk of vascular disease: meta-analysis of individual data from 27 randomised trials

This meta-analysis of individual patient data concluded that in individuals with five-year risk of major vascular events lower than 10%, each 1mmol/L reduction in low-density lipoprotein cholesterol produced an absolute reduction in major vascular events of about 11 per 1,000 over five years. The authors' conclusions are likely to be reliable.

Database of Abstracts of Reviews of Effects (DARE): Quality-assessed Reviews [Internet] - Centre for Reviews and Dissemination (UK).

Version: 2012

Comparing Newer Antiplatelet Agents

How do antiplatelet agents compare in acute coronary syndromes managed medically?

PubMed Clinical Q&A [Internet] - National Center for Biotechnology Information (US).

Version: November 10, 2011

A meta-analysis of the outcome of endovascular and noninvasive therapies in the treatment of intermittent claudication

PURPOSE: Intermittent claudication is a common symptom of peripheral arterial disease. Currently, there is a lack of consensus on the most effective therapies for this problem. We conducted a meta-analysis of randomized trials assessing the efficacy of endovascular therapy (EVT) compared with noninvasive therapies for the treatment of intermittent claudication.

Database of Abstracts of Reviews of Effects (DARE): Quality-assessed Reviews [Internet] - Centre for Reviews and Dissemination (UK).

Version: 2011

[Effectiveness of therapeutic physical exercise in patients with intermittent claudication due to peripheral arterial disease: a review]

Bibliographic details: Cebria Iranzo MA, Sentandreu Mano T, Baviera Ricart MC, Igual Camacho C.  [Effectiveness of therapeutic physical exercise in patients with intermittent claudication due to peripheral arterial disease: a review]. [Efectividad del ejercicio fisico terapeutico en pacientes con claudicacion intermitente por enfermedad arterial periferica: una revision.] Fisioterapia 2010; 32(4): 172-182

Database of Abstracts of Reviews of Effects (DARE): Quality-assessed Reviews [Internet] - Centre for Reviews and Dissemination (UK).

Version: 2010

Subintimal angioplasty: meta-analytical evidence of clinical utility

The authors concluded that subintimal angioplasty had good outcomes and should be considered as an alternative surgical bypass. The authors' conclusions may not be reliable given potential methodological weaknesses of the review and primary studies and the risk of publication bias.

Database of Abstracts of Reviews of Effects (DARE): Quality-assessed Reviews [Internet] - Centre for Reviews and Dissemination (UK).

Version: 2009

Ginkgo biloba special extract EGb 761 in the treatment of peripheral arterial occlusive disease (PAOD): a review based on randomized, controlled studies

OBJECTIVE: The present review gives an overview and evaluation of clinical studies proving the efficacy of EGb 761 in patients with PAOD.

Database of Abstracts of Reviews of Effects (DARE): Quality-assessed Reviews [Internet] - Centre for Reviews and Dissemination (UK).

Version: 2004

Dacron vs. PTFE as bypass materials in peripheral vascular surgery: systematic review and meta-analysis

This review found no evidence of a difference between polytetrafluoroethylene and polyester (Dacron) grafts in peripheral vascular surgery. The conclusions were supported by the results presented, but should be interpreted with caution due to the unclear quality of the included studies and possibility of publication bias.

Database of Abstracts of Reviews of Effects (DARE): Quality-assessed Reviews [Internet] - Centre for Reviews and Dissemination (UK).

Version: 2008

Medical Encyclopedia

  • Collagen vascular disease
    Collagen vascular disease occurs when problems with the immune system affect collagen.
  • Mesenteric artery ischemia
    Mesenteric artery ischemia occurs when there is a narrowing or blockage of one or more of the three major arteries that supply the small and large intestines. These are called the mesenteric arteries.
  • Peripheral artery disease - legs
    Peripheral artery disease is a condition of the blood vessels. It leads to narrowing and hardening of the arteries that supply the legs and feet.
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Systematic Reviews in PubMed

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