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Results: 3

Asking men to pass a catheter into their own urethra to try to stop a urethral stricture from coming back

About one in 300 men are affected by a condition called urethral stricture where part of the urethra scars causing it to become narrow. Most urethral strictures are caused by injury or infection. The main symptom is difficulty passing urine. In at least half of patients, urethral strictures come back within two years after they have a surgical operation called optical urethrotomy to stretch their urethral stricture. For this reason there is considerable interest in finding ways to reduce the chance of a urethral stricture coming back.

Cochrane Database of Systematic Reviews: Plain Language Summaries [Internet] - John Wiley & Sons, Ltd.

Version: 2015

Blind stretching or telescopic cutting versus open surgery for urethral narrowing in men

Narrowing of the urine pipe (urethral stricture) is a common cause of problems in passing water for younger men. Standard treatment consists of widening the strictured segment using instruments passed down the urethra (called urethral dilatation or urethrotomy). Alternatively, a urethroplasty operation can be performed whereby the narrowed area is removed or replaced by graft material. The uncertainty as to which option is best prompted this review of the current evidence. We found very little good quality evidence and were unable to achieve all our objectives for this review. The results of a single study suggest that dilatation and urethrotomy offer equivalent outcomes, but they are associated with a high rate of recurrence of the stricture requiring repeated procedures over a relatively short period of time. Preliminary data reported in abstract form suggested that urethroplasty was more effective than urethrotomy for the specific circumstance of urethral trauma following fracture of the pelvic bones. We found no data concerning well‐being or the quality of life amongst men treated for urethral stricture disease. The main conclusion of the review is that the current lack of quality evidence means that further trials are needed to establish which intervention is most effective and most cost‐effective for treatment of urethral stricture disease in men. 

Cochrane Database of Systematic Reviews: Plain Language Summaries [Internet] - John Wiley & Sons, Ltd.

Version: 2012

Cryotherapy for localised prostate cancer

Cryotherapy is a relatively new procedure for the treatment of localised prostate cancer. Under anaesthesia, probes are inserted into the prostate tumour that freeze the tissue, thereby killing tumour cells. This procedure is carried out on a day‐patient basis and generally patients are allowed home the following day. The main complications associated with cryotherapy include impotence (inability to maintain an erection), incontinence, and tissue sloughing (making urination difficult). Studies report that cryotherapy has potential clinical benefits for many patients with no evidence of cancer postoperatively; however, the quality of the available evidence is poor.

Cochrane Database of Systematic Reviews: Plain Language Summaries [Internet] - John Wiley & Sons, Ltd.

Version: 2012

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