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BtA injections provide more objective and subjective benefit than trihexyphenidyl to patients with cervical dystonia.

Cervical dystonia is characterized by involuntary posturing of the head and frequently is associated with neck pain. Disability and social withdrawal are common. Botulinum toxin Type A (BtA) is now the first line therapy but previously anticholinergics were the most widely accepted treatment. This review demonstrated that BtA injections are better than trihexyphenidyl, reduce involuntary muscular movements and tremor, reduce pain, and have fewer adverse effects as measured by objective scales and subjectively by patients.

Cochrane Database of Systematic Reviews: Plain Language Summaries [Internet] - John Wiley & Sons, Ltd.

Version: 2009

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