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Treats chronic myeloid leukemia (CML). This is an antineoplastic (cancer) medicine.

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Results: 3

Treatments for chronic myeloid leukemia: a qualitative systematic review

BACKGROUND: Chronic myeloid leukemia (CML) is a myeloproliferative disorder of blood stem cells. The tyrosine kinase inhibitor (TKI) imatinib was the first targeted therapy licensed for patients with chronic-phase CML, and its introduction was associated with substantial improvements in response and survival compared with previous therapies. Clinical trial data are now available for the second-generation TKIs (nilotinib, dasatinib, and bosutinib) in the first-, second-, and third-line settings. A qualitative systematic review was conducted to qualitatively compare the clinical effectiveness, safety, and effect on quality of life of TKIs for the management of chronic-, accelerated-, or blast-phase CML patients.

Database of Abstracts of Reviews of Effects (DARE): Quality-assessed Reviews [Internet] - Centre for Reviews and Dissemination (UK).

Version: 2012

Chronic Myelogenous Leukemia Treatment (PDQ®): Health Professional Version

Expert-reviewed information summary about the treatment of chronic myelogenous leukemia.

PDQ Cancer Information Summaries [Internet] - National Cancer Institute (US).

Version: May 23, 2014

Childhood Acute Myeloid Leukemia/Other Myeloid Malignancies Treatment (PDQ®): Health Professional Version

Expert-reviewed information summary about the treatment of childhood acute myeloid leukemia, myelodysplastic syndromes, and other myeloproliferative disorders.

PDQ Cancer Information Summaries [Internet] - National Cancer Institute (US).

Version: August 15, 2014

Systematic Reviews in PubMed

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