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Results: 3

Initial antibiotic treatment for coverage of 'atypical' pathogens for community‐acquired pneumonia in hospitalized adults

Pneumonia is a serious lung infection and is usually treated with antibiotics. Bacteria which cause community‐acquired pneumonia (CAP, pneumonia contracted outside healthcare settings) are traditionally divided into 'typical' and 'atypical', each dictating a different antibiotic treatment. Atypical bacteria include, Legionella pneumophila (L. pneumophila), Mycoplasma pneumoniae (M. pneumoniae) and Chlamydia pneumoniae (C. pneumoniae). The main 'typical' agent causing CAP is Streptococcus pneumoniae (S. pneumoniae). It is usually not possible to determine which of the many potential agents is the cause of CAP, so that antibiotic treatment is empirical, customarily covering both typical and atypical bacteria. While typical coverage is essential, the necessity of the atypical coverage has not been proven. In the previous version of this review we showed that there was no advantage to the atypical arm. Given the persisting inconsistency between current guidelines for treatment of pneumonia and the available evidence, we undertook to update this systematic review.

Cochrane Database of Systematic Reviews: Plain Language Summaries [Internet] - John Wiley & Sons, Ltd.

Version: 2012

Methotrexate for treatment of chronic active ulcerative colitis

Ulcerative colitis is a long‐term (chronic) inflammatory bowel disease characterized by pains (abdominal cramping), a need to rush to the toilet to pass feces (fecal urgency) and bloody diarrhea.

Cochrane Database of Systematic Reviews: Plain Language Summaries [Internet] - John Wiley & Sons, Ltd.

Version: 2014

Unusual Cancers of Childhood (PDQ®): Patient Version

Expert-reviewed information summary about the treatment of unusual cancers of childhood such as cancers of the head and neck, chest, abdomen, reproductive system, skin, and others.

PDQ Cancer Information Summaries [Internet] - National Cancer Institute (US).

Version: December 11, 2014

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