Home > Search Results
  • We are sorry, but NCBI web applications do not support your browser and may not function properly. More information

Results: 1 to 20 of 502

The effects of exercise on body weight and composition in breast cancer survivors: an integrative systematic review

PURPOSE/OBJECTIVES: To examine the research literature regarding the effects of exercise on body weight and composition in breast cancer survivors.

Database of Abstracts of Reviews of Effects (DARE): Quality-assessed Reviews [Internet] - Centre for Reviews and Dissemination (UK).

Version: 2006

Oral contraceptive use and breast or ovarian cancer risk in BRCA1/2 carriers: a meta-analysis

BACKGROUND: Women with BRCA1 or BRCA2 mutations are at increased risk of breast and ovarian cancer. Oral contraceptives (OC) use has been associated with a reduction in ovarian cancer risk and with a moderately increased breast cancer risk, which tends to level off in the few years after stopping. The association between oral contraceptive and BRCA1 or BRCA2 gene mutations carriers is unclear.

Database of Abstracts of Reviews of Effects (DARE): Quality-assessed Reviews [Internet] - Centre for Reviews and Dissemination (UK).

Version: 2010

Breast-conserving surgery with or without radiotherapy in women with ductal carcinoma in situ: a meta-analysis of randomized trials

This review concluded that compared with excision alone, addition of radiotherapy to lumpectomy led to a reduction in risk of a local in-breast recurrence, but there was no benefit for survival or distant metastasis. This review was generally well conducted. The conclusions are likely to be reliable.

Database of Abstracts of Reviews of Effects (DARE): Quality-assessed Reviews [Internet] - Centre for Reviews and Dissemination (UK).

Version: 2007

Breast cancer: What treatments have been shown to offer relief for lymphedema after breast cancer?

Self-management with compression bandaging can help reduce lymphedema after breast cancer. Professional manual lymphatic drainage might help as well. Because lymphedema often gets worse and harder to treat over time, early recognition of the problem is important.

Informed Health Online [Internet] - Institute for Quality and Efficiency in Health Care (IQWiG).

Version: November 21, 2013

The efficacy of mindfulness-based stress reduction on mental health of breast cancer patients: a meta-analysis

OBJECTIVE: This study aims to investigate the evidence of the efficacy of mindfulness-based stress reduction (MBSR) in improving stress, depression and anxiety in breast cancer patients.

Database of Abstracts of Reviews of Effects (DARE): Quality-assessed Reviews [Internet] - Centre for Reviews and Dissemination (UK).

Version: 2013

Effects of chemotherapy and hormonal therapy for early breast cancer on recurrence and 15-year survival: an overview of the randomised trials

This meta-analysis assessed the long-term effects of systemic adjuvant therapies on breast cancer recurrence and survival. The authors concluded that the breast cancer mortality rate could be halved with anthracycline-based chemotherapy followed by 5 years of adjuvant tamoxifen in middle-aged women with oestrogen receptor-positive disease. The thoroughness of this individual patient data analysis suggests that the conclusions are likely to be reliable.

Database of Abstracts of Reviews of Effects (DARE): Quality-assessed Reviews [Internet] - Centre for Reviews and Dissemination (UK).

Version: 2005

Use of pharmacologic interventions for breast cancer risk reduction: american society of clinical oncology clinical practice guideline

PURPOSE: To update the 2009 American Society of Clinical Oncology guideline on pharmacologic interventions for breast cancer (BC) risk reduction.

Database of Abstracts of Reviews of Effects (DARE): Quality-assessed Reviews [Internet] - Centre for Reviews and Dissemination (UK).

Version: 2013

Mindfulness-based stress reduction for breast cancer: a systematic review and meta-analysis

OBJECTIVE: The aim of this systematic review and meta-analysis was to assess the effectiveness of mindfulness-based stress reduction (mbsr) and mindfulness-based cognitive therapy (mbct) in patients with breast cancer.

Database of Abstracts of Reviews of Effects (DARE): Quality-assessed Reviews [Internet] - Centre for Reviews and Dissemination (UK).

Version: 2012

Autologous stem cell transplantation for breast cancer: Executive summary of final report N05-03E, Version 1.0

The aims of this investigation were to assess studies on certain types of autologous stem cell transplantation in breast cancer patients: compared to cytostatic therapy without stem cell support, and compared with each other.

Institute for Quality and Efficiency in Health Care: Executive Summaries [Internet] - Institute for Quality and Efficiency in Health Care (IQWiG).

Version: October 15, 2009

Intermittent pneumatic compression pump for breast cancer-related lymphedema: a systematic review and meta-analysis of randomized controlled trials

Background: Breast cancer-related lymphedema (BCRL) is a common complication after the treatment of breast cancer. The objective of this study was to determine whether the use of an intermittent pneumatic pump (IPC) could manage lymphedema effectively. Methods: We searched PubMed, EMBASE, and the Cochrane Library for related trials to compare the percent of volume reduction and subjective symptoms. Results: 7 randomized controlled trials, with 287 patients, were included. Results showed that the use of the IPC could alleviate lymphedema, but no significant difference between routine management of lymphedema with or without pneumatic pump existed. Conclusion: Current trials fail to show the effectiveness of the addition of an IPC to the routine management of BCRL. © 2014 S. Karger GmbH, Freiburg.

Database of Abstracts of Reviews of Effects (DARE): Quality-assessed Reviews [Internet] - Centre for Reviews and Dissemination (UK).

Version: 2014

Impact on survival of early detection of isolated breast recurrences after the primary treatment for breast cancer: a meta-analysis

This review supported the hypothesis that detection of isolated loco-regional or contra-lateral breast cancer recurrences in patients without symptoms has a beneficial effect on survival compared to late symptomatic detection. The review appeared generally well-conducted and the authors' conclusions are likely to be reliable.

Database of Abstracts of Reviews of Effects (DARE): Quality-assessed Reviews [Internet] - Centre for Reviews and Dissemination (UK).

Version: 2009

Capsular contracture in subglandular breast augmentation with textured versus smooth breast implants: a systematic review

The authors concluded that findings suggest that textured breast implants in subglandular breast augmentation reduce the risks of early capsular contracture compared with smooth implants, but more long-term research is required. Overall, this was a well-conducted review and the authors' cautious conclusions are likely to be reliable.

Database of Abstracts of Reviews of Effects (DARE): Quality-assessed Reviews [Internet] - Centre for Reviews and Dissemination (UK).

Version: 2006

Effects of physical activity on breast cancer prevention: a systematic review

BACKGROUND: Observational studies have reported an association between physical activity and breast cancer risk reduction. This study aims to evaluate the effect of physical activity on breast cancer prevention.

Database of Abstracts of Reviews of Effects (DARE): Quality-assessed Reviews [Internet] - Centre for Reviews and Dissemination (UK).

Version: 2014

Breast cancer screening for women ages 50 to 69 years a systematic review of observational evidence.

OBJECTIVE: To systematically review the observational evidence concerning the effect of screening on breast cancer mortality in actual populations of women ages 50-69 years.

Database of Abstracts of Reviews of Effects (DARE): Quality-assessed Reviews [Internet] - Centre for Reviews and Dissemination (UK).

Version: 2011

Adjuvant trastuzumab in elderly with HER-2 positive breast cancer: a systematic review of randomized controlled trials

Trastuzumab, in combination with chemotherapy, is the gold standard in the adjuvant treatment of patients with HER2 positive breast cancer. Limited data are available on the role of adjuvant trastuzumab in the elderly population. We performed a systematic review of prospective randomized trials with available data on the use of adjuvant trastuzumab in patients older than 60years, focusing on both the efficacy and the cardiac safety. Data extrapolated from two prospective trials were included for efficacy and cardiac safety. A significant 47% relative risk reduction was observed in elderly patients receiving trastuzumab compared to chemotherapy alone (pooled Hazard Ratio: 0.53; 95% CI, 0.36-0.77). The pooled proportion of cardiac events in elderly patients treated with trastuzumab was 5% (95% CI, 4-7%). The use of trastuzumab should be considered as a standard of care in the adjuvant therapy of elderly patients with HER-2 positive breast cancer. Acute and chronic medical conditions, nutritional status and level of daily activities should be considered. Uncertainty about cardiac safety in the elderly is a major concern.

Database of Abstracts of Reviews of Effects (DARE): Quality-assessed Reviews [Internet] - Centre for Reviews and Dissemination (UK).

Version: 2013

Weekly schedule of docetaxel in breast cancer: evaluation of response and toxicity

Several recent studies have investigated the administration of docetaxel on a weekly basis. Here, we review the weekly use of docetaxel in breast cancer. To identify articles published on this topic we performed a computer-assisted MEDLINE search; additional references were found in the bibliographies of these articles. Several phase Tstudies of weekly docetaxel have provided encouraging data indicating that there is generally less myelosuppression than with the three week schedule in patients with a variety of advanced malignancies. Dose-limiting toxicities are reached at 43 to 50 mg/m(2), and the recommended dose ranges from 36 to 42 mg/m(2). Furthermore, five studies of weekly docetaxel in patients with metastatic breast cancer achieved 32 to 41% response rates using 25 to 40 mg/m(2) of docetaxel. Myelosuppression was mild, but fatigue was common and was the most common reason for dose reduction. In general, the planned dose intensity was equivalent to those used in standard three week schedules, and fatigue, asthenia, nail changes, excessive lacrimation (tearing), and fluid retention became more common with prolonged administration of docetaxel. Thus, weekly scheduling of docetaxel maintains efficacy and alters the toxicity profile, and the use of weekly docetaxel will become a promising alternative to three week dosing in the treatment of advanced breast cancer once randomized controlled studies confirm these results. However, there is still much to learn about the role of weekly docetaxel in adjuvant and neoadjuvant therapy.

Database of Abstracts of Reviews of Effects (DARE): Quality-assessed Reviews [Internet] - Centre for Reviews and Dissemination (UK).

Version: 2003

Are systemic antibiotics indicated in aesthetic breast surgery? A systematic review of the literature

BACKGROUND: The use of systemic prophylactic antibiotics to reduce surgical-site infection in aesthetic breast surgery remains controversial. The aim of this review is to weigh the available evidence with respect to reducing surgical-site infection.

Database of Abstracts of Reviews of Effects (DARE): Quality-assessed Reviews [Internet] - Centre for Reviews and Dissemination (UK).

Version: 2013

Microsurgical techniques for the treatment of breast cancer-related lymphedema: a systematic review

BACKGROUND: Upper limb lymphedema is one of the most underestimated and debilitating complications of breast cancer treatment. The aim of this review is to summarize the recent literature for evidence of the effectiveness of lymphatic microsurgery for the treatment of breast cancer-related lymphedema (BCRL).

Database of Abstracts of Reviews of Effects (DARE): Quality-assessed Reviews [Internet] - Centre for Reviews and Dissemination (UK).

Version: 2013

Association between NSAIDs use and breast cancer risk: a systematic review and meta-analysis

This review concluded that the incidence of breast cancer in women was slightly reduced by the use of non-steroidal anti-inflammatory drugs. Given substantial flaws in the methodology and analysis, and the presence of publication bias, this conclusion should be treated with extreme caution.

Database of Abstracts of Reviews of Effects (DARE): Quality-assessed Reviews [Internet] - Centre for Reviews and Dissemination (UK).

Version: 2009

CT-angiography prior to DIEP flap breast reconstruction: a systematic review and meta-analysis

BACKGROUND: Preoperative CT-angiography (CTA) has shown to reduce operative time in deep inferior epigastric perforator (DIEP) flap breast reconstruction compared to Doppler ultrasonography (US). Although decreased flap loss has been suggested, statistical significant reduction remains indeterminate. The purpose of this review is to evaluate flap loss after preoperative CTA and Doppler US in DIEP-flap breast reconstruction.

Database of Abstracts of Reviews of Effects (DARE): Quality-assessed Reviews [Internet] - Centre for Reviews and Dissemination (UK).

Version: 2013

Medical Encyclopedia

  • Breast lift
    A breast lift, or mastopexy, is cosmetic breast surgery to lift the breasts. The surgery may also involve changing the position of the areola and nipple.
  • Breast reduction (mammoplasty) - series
    Breast reduction is usually performed for enlarged breasts (macromastia), but may also be indicated by:
  • Breast reduction
    Breast reduction is surgery to reduce the size of the breasts.
See all (10)...

Systematic Reviews in PubMed

See all (520)...

Recent Activity

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

See more...