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1963 1
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29 results

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Page 1
In-vitro neuroprotective effect and mechanism of 2beta-hydroxy-delta-cadinol against amyloid beta-induced neuronal apoptosis.
Ji ZH, Zhao H, Liu C, Yu XY. Ji ZH, et al. Neuroreport. 2020 Feb 5;31(3):245-250. doi: 10.1097/WNR.0000000000001398. Neuroreport. 2020. PMID: 31895745
In our previous study, a sesquiterpenoid compound 2beta-hydroxy-delta-cadinol (HOC) which exhibited antiglutamate excitotoxicity effect was isolated from the fruits of Alpinia oxyphylla Miquel. ...
In our previous study, a sesquiterpenoid compound 2beta-hydroxy-delta-cadinol (HOC) which exhibited antiglutamate excitotoxici …
Identification and Characterization of a delta-Cadinol Synthase Potentially Involved in the Formation of Boreovibrins in Boreostereum vibrans of Basidiomycota.
Zhou H, Yang YL, Zeng J, Zhang L, Ding ZH, Zeng Y. Zhou H, et al. Nat Prod Bioprospect. 2016 Jun;6(3):167-71. doi: 10.1007/s13659-016-0096-4. Epub 2016 Apr 1. Nat Prod Bioprospect. 2016. PMID: 27038475 Free PMC article.
A large number of sesquiterpene synthase genes have been cloned and functionally characterized. However, until now there is no report about the delta-cadinol synthase predominantly forming delta-cadinol (syn. torreyol) from farnesyl diphosphate. ...The …
A large number of sesquiterpene synthase genes have been cloned and functionally characterized. However, until now there is no report about …
Biotechnological potential and initial characterization of two novel sesquiterpene synthases from Basidiomycota Coniophora puteana for heterologous production of delta-cadinol.
Ringel M, Dimos N, Himpich S, Haack M, Huber C, Eisenreich W, Schenk G, Loll B, Brück T. Ringel M, et al. Microb Cell Fact. 2022 Apr 19;21(1):64. doi: 10.1186/s12934-022-01791-8. Microb Cell Fact. 2022. PMID: 35440053 Free PMC article.
RESULTS: In this study we describe the identification of two novel (+)-delta-cadinol synthases from C. puteana, Copu5 and Copu9. The sesquiterpene (+)-delta-cadinol was previously shown to exhibit cytotoxic activity therefore having an application as p …
RESULTS: In this study we describe the identification of two novel (+)-delta-cadinol synthases from C. puteana, Copu5 and Copu …
In vitro Applications of the Terpene Mini-Path 2.0.
Couillaud J, Amouric A, Courvoisier-Dezord E, Leydet L, Schweitzer N, Rosso MN, Hage H, Loussouarn-Yvon M, Vincentelli R, Petit JL, de Berardinis V, Attolini M, Maresca M, Duquesne K, Iacazio G. Couillaud J, et al. Chembiochem. 2022 Dec 16;23(24):e202200595. doi: 10.1002/cbic.202200595. Epub 2022 Nov 17. Chembiochem. 2022. PMID: 36269004
Functional characterisation of twelve terpene synthases from actinobacteria.
Chhalodia AK, Xu H, Tabekoueng GB, Gu B, Taizoumbe KA, Lauterbach L, Dickschat JS. Chhalodia AK, et al. Beilstein J Org Chem. 2023 Sep 15;19:1386-1398. doi: 10.3762/bjoc.19.100. eCollection 2023. Beilstein J Org Chem. 2023. PMID: 37736393 Free PMC article.
For four enzymes with functions not previously reported from bacterial terpene synthases the products were isolated and their structures were elucidated by NMR spectroscopy, resulting in the discovery of the first terpene synthases for (+)-delta-cadinol and (+)-alph …
For four enzymes with functions not previously reported from bacterial terpene synthases the products were isolated and their structures wer …
Deciphering the antifungal mechanism and functional components of cinnamomum cassia essential oil against Candida albicans through integration of network-based metabolomics and pharmacology, the greedy algorithm, and molecular docking.
Gu K, Feng S, Zhang X, Peng Y, Sun P, Liu W, Wu Y, Yu Y, Liu X, Liu X, Deng G, Zheng J, Li B, Zhao L. Gu K, et al. J Ethnopharmacol. 2024 Jan 30;319(Pt 2):117156. doi: 10.1016/j.jep.2023.117156. Epub 2023 Sep 18. J Ethnopharmacol. 2024. PMID: 37729978
Six antifungal functional components of CEO were identified through network construction, greedy algorithm and molecular docking, including trans-cinnamaldehyde, delta-cadinol, ethylcinnamate, safrole, trans-anethole, and trans-cinnamyl acetate, which showed excelle …
Six antifungal functional components of CEO were identified through network construction, greedy algorithm and molecular docking, including …
Molecular and Functional Analyses of Characterized Sesquiterpene Synthases in Mushroom-Forming Fungi.
Wang S, Chen R, Yuan L, Zhang C, Liang D, Qiao J. Wang S, et al. J Fungi (Basel). 2023 Oct 14;9(10):1017. doi: 10.3390/jof9101017. J Fungi (Basel). 2023. PMID: 37888273 Free PMC article.
Finally, three FvSTSs were selected to experimentally characterize their functions. FvSTS03 predominantly produced delta-cadinol and FvSTS08 synthesized beta-barbatene as the main product; these findings were consistent with those of the functional prediction analys …
Finally, three FvSTSs were selected to experimentally characterize their functions. FvSTS03 predominantly produced delta-cadinol …
Essential oil composition and anti Acanthamoeba studies of Teucrium ramosissimum.
Ghazouani N, Sifaoui I, Bachrouch O, Abderrabba M, E Pinero J, Lorenzo-Morales J. Ghazouani N, et al. Exp Parasitol. 2017 Dec;183:207-211. doi: 10.1016/j.exppara.2017.09.010. Epub 2017 Sep 12. Exp Parasitol. 2017. PMID: 28916455
Sixty-eight compounds representing 97.78% of the essential oil were identified, of which delta-cadinene (18.63%), delta-cadinol (18.70%), beta-eudesmol (12.13%), gamma-gurjunene (4.34%) and 8-cedrene (3.99%) were the main compounds. ...
Sixty-eight compounds representing 97.78% of the essential oil were identified, of which delta-cadinene (18.63%), delta-cadinol …
Five new cadinane-type sesquiterpenes from the heartwood of Chamaecyparis obtusa var. formosana.
Kuo YH, Chen CH, Chien SC, Lin YL. Kuo YH, et al. J Nat Prod. 2002 Jan;65(1):25-8. doi: 10.1021/np0101402. J Nat Prod. 2002. PMID: 11809059
Muurola-4,10(14)-dien-3-one (1), 10-O-acetyl-15-oxo-alpha-cadinol (2), 15-hydroxy-alpha-cadinol (3), 4alpha-hydroxy-5beta-ethoxy-epi-cubenol (4), and 4alpha-hydroxy-5beta-acetoxy-epi-cubenol (5), five new bicyclic sesquiterpenes, have been isolated from the heartwood of Chamaecyp …
Muurola-4,10(14)-dien-3-one (1), 10-O-acetyl-15-oxo-alpha-cadinol (2), 15-hydroxy-alpha-cadinol (3), 4alpha-hydroxy-5beta-ethoxy-epi-cubenol …
29 results