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Showing results for zygotic
Your search for zymogic retrieved no results
The maternal to zygotic transition in mammals.
Li L, Lu X, Dean J. Li L, et al. Mol Aspects Med. 2013 Oct;34(5):919-38. doi: 10.1016/j.mam.2013.01.003. Epub 2013 Jan 23. Mol Aspects Med. 2013. PMID: 23352575 Free PMC article. Review.
Following gamete union, the transcriptionally inert sperm DNA is repackaged into the male pronucleus which fuses with the female pronucleus to form a 1-cell zygote. Embryonic transcription begins during the maternal to zygotic transfer of control in directing develo …
Following gamete union, the transcriptionally inert sperm DNA is repackaged into the male pronucleus which fuses with the female pronucleus …
Zygotic gene activation in mice: profile and regulation.
Aoki F. Aoki F. J Reprod Dev. 2022 Apr 1;68(2):79-84. doi: 10.1262/jrd.2021-129. Epub 2022 Jan 15. J Reprod Dev. 2022. PMID: 35034936 Free PMC article. Review.
The zygotic genome is transcriptionally silent immediately after fertilization. ...These two phases of gene activation are called minor and major zygotic gene activation (ZGA), respectively. As they mark the beginning of the gene expression program, it is important …
The zygotic genome is transcriptionally silent immediately after fertilization. ...These two phases of gene activation are called min …
Germ cell-specific eIF4E1b regulates maternal mRNA translation to ensure zygotic genome activation.
Yang G, Xin Q, Feng I, Wu D, Dean J. Yang G, et al. Genes Dev. 2023 May 1;37(9-10):418-431. doi: 10.1101/gad.350400.123. Epub 2023 May 31. Genes Dev. 2023. PMID: 37257918 Free PMC article.
Translation of maternal mRNAs is detected before transcription of zygotic genes and is essential for mammalian embryo development. How certain maternal mRNAs are selected for translation instead of degradation and how this burst of translation affects zygotic genome …
Translation of maternal mRNAs is detected before transcription of zygotic genes and is essential for mammalian embryo development. Ho …
Profiling and functional characterization of maternal mRNA translation during mouse maternal-to-zygotic transition.
Zhang C, Wang M, Li Y, Zhang Y. Zhang C, et al. Sci Adv. 2022 Feb 4;8(5):eabj3967. doi: 10.1126/sciadv.abj3967. Epub 2022 Feb 2. Sci Adv. 2022. PMID: 35108058 Free PMC article.
We identified a marked translational transition from MII oocytes to zygotes and demonstrated that active translation of maternal mRNAs is essential for maternal-to-zygotic transition (MZT). We further showed that two maternal factors, Smarcd2 and Cyclin T2, whose tr …
We identified a marked translational transition from MII oocytes to zygotes and demonstrated that active translation of maternal mRNA …
Control of zygotic genome activation in Xenopus.
Blitz IL, Cho KWY. Blitz IL, et al. Curr Top Dev Biol. 2021;145:167-204. doi: 10.1016/bs.ctdb.2021.03.003. Epub 2021 Apr 19. Curr Top Dev Biol. 2021. PMID: 34074529 Free PMC article. Review.
The fertilized frog egg contains all the materials needed to initiate development of a new organism, including stored RNAs and proteins deposited during oogenesis, thus the earliest stages of development do not require transcription. The onset of transcription from the zygotic …
The fertilized frog egg contains all the materials needed to initiate development of a new organism, including stored RNAs and proteins depo …
Zygotic genome activation in the chicken: a comparative review.
Rengaraj D, Hwang YS, Lee HC, Han JY. Rengaraj D, et al. Cell Mol Life Sci. 2020 May;77(10):1879-1891. doi: 10.1007/s00018-019-03360-6. Epub 2019 Nov 15. Cell Mol Life Sci. 2020. PMID: 31728579 Free PMC article. Review.
After fertilization, these maternal factors are cleared and embryonic development is determined by an individual's own RNAs and proteins, in a process called the maternal-to-zygotic transition. Zygotic transcription is initially inactive, but is eventually activated …
After fertilization, these maternal factors are cleared and embryonic development is determined by an individual's own RNAs and proteins, in …
The timing of zygotic genome activation.
Pálfy M, Joseph SR, Vastenhouw NL. Pálfy M, et al. Curr Opin Genet Dev. 2017 Apr;43:53-60. doi: 10.1016/j.gde.2016.12.001. Epub 2017 Jan 12. Curr Opin Genet Dev. 2017. PMID: 28088031 Review.
After fertilization, the embryonic genome is inactive until transcription is initiated during the maternal-to-zygotic transition. How the onset of transcription is regulated in a precisely timed manner, however, is a long standing question in biology. ...
After fertilization, the embryonic genome is inactive until transcription is initiated during the maternal-to-zygotic transition. How …
Zygotic Nuclear F-Actin Safeguards Embryonic Development.
Okuno T, Li WY, Hatano Y, Takasu A, Sakamoto Y, Yamamoto M, Ikeda Z, Shindo T, Plessner M, Morita K, Matsumoto K, Yamagata K, Grosse R, Miyamoto K. Okuno T, et al. Cell Rep. 2020 Jun 30;31(13):107824. doi: 10.1016/j.celrep.2020.107824. Cell Rep. 2020. PMID: 32610125 Free article.
After fertilization, sperm and oocyte nuclei are rapidly remodeled to form swollen pronuclei (PN) in mammalian zygotes, and the proper formation and function of PN are key to producing totipotent zygotes. ...We show that nuclear F-actin ensures DNA damage repair, th …
After fertilization, sperm and oocyte nuclei are rapidly remodeled to form swollen pronuclei (PN) in mammalian zygotes, and the prope …
Zygotic Genome Activation Revisited: Looking Through the Expression and Function of Zscan4.
Ko MS. Ko MS. Curr Top Dev Biol. 2016;120:103-24. doi: 10.1016/bs.ctdb.2016.04.004. Epub 2016 May 31. Curr Top Dev Biol. 2016. PMID: 27475850 Review.
Zygotic genome activation (ZGA, a.k.a. zygotic gene activation) is a critical event in development, when the paternally derived genome and maternally derived genome begin to be activated and transcribed after fertilization. ...
Zygotic genome activation (ZGA, a.k.a. zygotic gene activation) is a critical event in development, when the paternally derive …
Setting the stage for development: the maternal-to-zygotic transition in Drosophila.
Harrison MM, Marsh AJ, Rushlow CA. Harrison MM, et al. Genetics. 2023 Oct 4;225(2):iyad142. doi: 10.1093/genetics/iyad142. Genetics. 2023. PMID: 37616526 Review.
The zygote has a daunting task ahead of itself; it must develop from a single cell (fertilized egg) into a fully functioning adult with a multitude of different cell types. ...The transfer of developmental control from the mother to the embryo is called the maternal-to- …
The zygote has a daunting task ahead of itself; it must develop from a single cell (fertilized egg) into a fully functioning adult wi …
18,909 results
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