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Direct Reprogramming of Human Primordial Germ Cells into Induced Pluripotent Stem Cells: Efficient Generation of Genetically Engineered Germ Cells.

Bazley FA, Liu CF, Yuan X, Hao H, All AH, De Los Angeles A, Zambidis ET, Gearhart JD, Kerr CL.

Stem Cells Dev. 2015 Aug 10. [Epub ahead of print]


Gaucher Disease-Induced Pluripotent Stem Cells Display Decreased Erythroid Potential and Aberrant Myelopoiesis.

Sgambato JA, Park TS, Miller D, Panicker LM, Sidransky E, Lun Y, Awad O, Bentzen SM, Zambidis ET, Feldman RA.

Stem Cells Transl Med. 2015 Aug;4(8):878-86. doi: 10.5966/sctm.2014-0213. Epub 2015 Jun 10.


Cancer-like epigenetic derangements of human pluripotent stem cells and their impact on applications in regeneration and repair.

Huo JS, Baylin SB, Zambidis ET.

Curr Opin Genet Dev. 2014 Oct;28:43-9. doi: 10.1016/j.gde.2014.09.008. Epub 2014 Oct 14. Review.


Automated grouping of action potentials of human embryonic stem cell-derived cardiomyocytes.

Gorospe G, Zhu R, Millrod MA, Zambidis ET, Tung L, Vidal R.

IEEE Trans Biomed Eng. 2014 Sep;61(9):2389-95. doi: 10.1109/TBME.2014.2311387.


Induced pluripotent stem cells from familial Alzheimer's disease patients differentiate into mature neurons with amyloidogenic properties.

Mahairaki V, Ryu J, Peters A, Chang Q, Li T, Park TS, Burridge PW, Talbot CC Jr, Asnaghi L, Martin LJ, Zambidis ET, Koliatsos VE.

Stem Cells Dev. 2014 Dec 15;23(24):2996-3010. doi: 10.1089/scd.2013.0511.


Generation of three-dimensional retinal tissue with functional photoreceptors from human iPSCs.

Zhong X, Gutierrez C, Xue T, Hampton C, Vergara MN, Cao LH, Peters A, Park TS, Zambidis ET, Meyer JS, Gamm DM, Yau KW, Canto-Soler MV.

Nat Commun. 2014 Jun 10;5:4047. doi: 10.1038/ncomms5047.


Gaucher iPSC-derived macrophages produce elevated levels of inflammatory mediators and serve as a new platform for therapeutic development.

Panicker LM, Miller D, Awad O, Bose V, Lun Y, Park TS, Zambidis ET, Sgambato JA, Feldman RA.

Stem Cells. 2014 Sep;32(9):2338-49. doi: 10.1002/stem.1732.


Dynamic Interactions Between Cancer Stem Cells And Their Stromal Partners.

Park TS, Donnenberg VS, Donnenberg AD, Zambidis ET, Zimmerlin L.

Curr Pathobiol Rep. 2014 Mar 1;2(1):41-52.


Vascular progenitors from cord blood-derived induced pluripotent stem cells possess augmented capacity for regenerating ischemic retinal vasculature.

Park TS, Bhutto I, Zimmerlin L, Huo JS, Nagaria P, Miller D, Rufaihah AJ, Talbot C, Aguilar J, Grebe R, Merges C, Reijo-Pera R, Feldman RA, Rassool F, Cooke J, Lutty G, Zambidis ET.

Circulation. 2014 Jan 21;129(3):359-72. doi: 10.1161/CIRCULATIONAHA.113.003000. Epub 2013 Oct 25.


Mesenchymal stem cell secretome and regenerative therapy after cancer.

Zimmerlin L, Park TS, Zambidis ET, Donnenberg VS, Donnenberg AD.

Biochimie. 2013 Dec;95(12):2235-45. doi: 10.1016/j.biochi.2013.05.010. Epub 2013 Jun 5. Review.


Highly efficient directed differentiation of human induced pluripotent stem cells into cardiomyocytes.

Burridge PW, Zambidis ET.

Methods Mol Biol. 2013;997:149-61. doi: 10.1007/978-1-62703-348-0_12.


Human induced pluripotent stem cell-derived endothelial cells exhibit functional heterogeneity.

Rufaihah AJ, Huang NF, Kim J, Herold J, Volz KS, Park TS, Lee JC, Zambidis ET, Reijo-Pera R, Cooke JP.

Am J Transl Res. 2013;5(1):21-35. Epub 2013 Jan 21.


HMGA1 reprograms somatic cells into pluripotent stem cells by inducing stem cell transcriptional networks.

Shah SN, Kerr C, Cope L, Zambidis E, Liu C, Hillion J, Belton A, Huso DL, Resar LM.

PLoS One. 2012;7(11):e48533. doi: 10.1371/journal.pone.0048533. Epub 2012 Nov 15.


Pivots of pluripotency: the roles of non-coding RNA in regulating embryonic and induced pluripotent stem cells.

Huo JS, Zambidis ET.

Biochim Biophys Acta. 2013 Feb;1830(2):2385-94. doi: 10.1016/j.bbagen.2012.10.014. Epub 2012 Oct 24. Review.


Induced pluripotent stem cell model recapitulates pathologic hallmarks of Gaucher disease.

Panicker LM, Miller D, Park TS, Patel B, Azevedo JL, Awad O, Masood MA, Veenstra TD, Goldin E, Stubblefield BK, Tayebi N, Polumuri SK, Vogel SN, Sidransky E, Zambidis ET, Feldman RA.

Proc Natl Acad Sci U S A. 2012 Oct 30;109(44):18054-9. doi: 10.1073/pnas.1207889109. Epub 2012 Oct 15.


Cardiomyocytes derived from human induced pluripotent stem cells as models for normal and diseased cardiac electrophysiology and contractility.

Blazeski A, Zhu R, Hunter DW, Weinberg SH, Zambidis ET, Tung L.

Prog Biophys Mol Biol. 2012 Oct-Nov;110(2-3):166-77. doi: 10.1016/j.pbiomolbio.2012.07.013. Epub 2012 Aug 7. Review.


Electrophysiological and contractile function of cardiomyocytes derived from human embryonic stem cells.

Blazeski A, Zhu R, Hunter DW, Weinberg SH, Boheler KR, Zambidis ET, Tung L.

Prog Biophys Mol Biol. 2012 Oct-Nov;110(2-3):178-95. doi: 10.1016/j.pbiomolbio.2012.07.012. Epub 2012 Aug 7. Review.


Growth factor-activated stem cell circuits and stromal signals cooperatively accelerate non-integrated iPSC reprogramming of human myeloid progenitors.

Park TS, Huo JS, Peters A, Talbot CC Jr, Verma K, Zimmerlin L, Kaplan IM, Zambidis ET.

PLoS One. 2012;7(8):e42838. doi: 10.1371/journal.pone.0042838. Epub 2012 Aug 8.


Efficient and simultaneous generation of hematopoietic and vascular progenitors from human induced pluripotent stem cells.

Park TS, Zimmerlin L, Zambidis ET.

Cytometry A. 2013 Jan;83(1):114-26. doi: 10.1002/cyto.a.22090. Epub 2012 Jun 26.


Engraftment of human embryonic stem cell derived cardiomyocytes improves conduction in an arrhythmogenic in vitro model.

Thompson SA, Burridge PW, Lipke EA, Shamblott M, Zambidis ET, Tung L.

J Mol Cell Cardiol. 2012 Jul;53(1):15-23. doi: 10.1016/j.yjmcc.2012.01.023. Epub 2012 Feb 10.

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