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Items: 1 to 20 of 73


Deficiency of programmed cell death 4 results in increased IL-10 expression by macrophages and thereby attenuates atherosclerosis in hyperlipidemic mice.

Jiang Y, Gao Q, Wang L, Guo C, Zhu F, Wang B, Wang Q, Gao F, Chen Y, Zhang L.

Cell Mol Immunol. 2015 Jul 13. doi: 10.1038/cmi.2015.47. [Epub ahead of print]


CD317 is over-expressed in B-cell chronic lymphocytic leukemia, but not B-cell acute lymphoblastic leukemia.

Gong S, Osei ES, Kaplan D, Chen YH, Meyerson H.

Int J Clin Exp Pathol. 2015 Feb 1;8(2):1613-21. eCollection 2015.


Exacerbated experimental colitis in TNFAIP8-deficient mice.

Sun H, Lou Y, Porturas T, Morrissey S, Luo G, Qi J, Ruan Q, Shi S, Chen YH.

J Immunol. 2015 Jun 15;194(12):5736-42. doi: 10.4049/jimmunol.1401986. Epub 2015 May 6.


Crucial roles of TNFAIP8 protein in regulating apoptosis and Listeria infection.

Porturas TP, Sun H, Buchlis G, Lou Y, Liang X, Cathopoulis T, Fayngerts S, Johnson DS, Wang Z, Chen YH.

J Immunol. 2015 Jun 15;194(12):5743-50. doi: 10.4049/jimmunol.1401987. Epub 2015 May 6.


TIPE2 protein prevents injury-induced restenosis in mice.

Zhang G, Zhao L, Wang Y, Shao J, Cui J, Lou Y, Geng M, Zhang N, Chen YH, Liu S.

Biochim Biophys Acta. 2015 Aug;1852(8):1574-84. doi: 10.1016/j.bbadis.2015.04.018. Epub 2015 Apr 22.


TIPE2 protein negatively regulates HBV-specific CD8⁺ T lymphocyte functions in humans.

Zhang W, Zhang J, Zhao L, Shao J, Cui J, Guo C, Zhu F, Chen YH, Liu S.

Mol Immunol. 2015 Mar;64(1):204-9. doi: 10.1016/j.molimm.2014.11.019. Epub 2014 Dec 12.


TIPE3 is the transfer protein of lipid second messengers that promote cancer.

Fayngerts SA, Wu J, Oxley CL, Liu X, Vourekas A, Cathopoulis T, Wang Z, Cui J, Liu S, Sun H, Lemmon MA, Zhang L, Shi Y, Chen YH.

Cancer Cell. 2014 Oct 13;26(4):465-78. doi: 10.1016/j.ccr.2014.07.025. Epub 2014 Sep 18.


Critical roles of TIPE2 protein in murine experimental colitis.

Lou Y, Sun H, Morrissey S, Porturas T, Liu S, Hua X, Chen YH.

J Immunol. 2014 Aug 1;193(3):1064-70. doi: 10.4049/jimmunol.1400415. Epub 2014 Jun 27.


Human tumor necrosis factor (TNF)-alpha-induced protein 8-like 2 suppresses hepatocellular carcinoma metastasis through inhibiting Rac1.

Cao X, Zhang L, Shi Y, Sun Y, Dai S, Guo C, Zhu F, Wang Q, Wang J, Wang X, Chen YH, Zhang L.

Mol Cancer. 2013 Nov 26;12(1):149. doi: 10.1186/1476-4598-12-149.


Enhanced atherosclerosis in TIPE2-deficient mice is associated with increased macrophage responses to oxidized low-density lipoprotein.

Lou Y, Liu S, Zhang C, Zhang G, Li J, Ni M, An G, Dong M, Liu X, Zhu F, Zhang W, Gao F, Chen YH, Zhang Y.

J Immunol. 2013 Nov 1;191(9):4849-57. doi: 10.4049/jimmunol.1300053. Epub 2013 Sep 30.


Downregulation of TIPE2 mRNA expression in peripheral blood mononuclear cells from patients with chronic hepatitis C.

Kong L, Liu K, Zhang YZ, Jin M, Wu BR, Wang WZ, Li W, Nan YM, Chen YH.

Hepatol Int. 2013 Jul;7(3):844-9. doi: 10.1007/s12072-013-9435-2. Epub 2013 Apr 5.


Tumor suppressor gene PDCD4 negatively regulates autophagy by inhibiting the expression of autophagy-related gene ATG5.

Song X, Zhang X, Wang X, Zhu F, Guo C, Wang Q, Shi Y, Wang J, Chen Y, Zhang L.

Autophagy. 2013 May;9(5):743-55. doi: 10.4161/auto.24069. Epub 2013 Mar 13.


TIPE2 deficiency accelerates neointima formation by downregulating smooth muscle cell differentiation.

Zhang G, Zhang W, Lou Y, Xi W, Cui J, Geng M, Zhu F, Chen YH, Liu S.

Cell Cycle. 2013 Feb 1;12(3):501-10. doi: 10.4161/cc.23325. Epub 2013 Jan 16.


TIPE2 protein serves as a negative regulator of phagocytosis and oxidative burst during infection.

Wang Z, Fayngerts S, Wang P, Sun H, Johnson DS, Ruan Q, Guo W, Chen YH.

Proc Natl Acad Sci U S A. 2012 Sep 18;109(38):15413-8. Epub 2012 Sep 4.


Smad3 binding to the foxp3 enhancer is dispensable for the development of regulatory T cells with the exception of the gut.

Schlenner SM, Weigmann B, Ruan Q, Chen Y, von Boehmer H.

J Exp Med. 2012 Aug 27;209(9):1529-35. doi: 10.1084/jem.20112646. Epub 2012 Aug 20.


TIPE2 controls innate immunity to RNA by targeting the phosphatidylinositol 3-kinase-Rac pathway.

Sun H, Zhuang G, Chai L, Wang Z, Johnson D, Ma Y, Chen YH.

J Immunol. 2012 Sep 15;189(6):2768-73. doi: 10.4049/jimmunol.1103477. Epub 2012 Aug 17.


Nuclear factor-κB binding motifs specify Toll-like receptor-induced gene repression through an inducible repressosome.

Yan Q, Carmody RJ, Qu Z, Ruan Q, Jager J, Mullican SE, Lazar MA, Chen YH.

Proc Natl Acad Sci U S A. 2012 Aug 28;109(35):14140-5. doi: 10.1073/pnas.1119842109. Epub 2012 Aug 13.


TIPE2, a novel regulator of immunity, protects against experimental stroke.

Zhang Y, Wei X, Liu L, Liu S, Wang Z, Zhang B, Fan B, Yang F, Huang S, Jiang F, Chen YH, Yi F.

J Biol Chem. 2012 Sep 21;287(39):32546-55. Epub 2012 Aug 2.


Ras family of small GTPases in immunity and inflammation.

Johnson DS, Chen YH.

Curr Opin Pharmacol. 2012 Aug;12(4):458-63. doi: 10.1016/j.coph.2012.02.003. Epub 2012 Mar 7. Review.


The anti-inflammatory TIPE2 is an inhibitor of the oncogenic Ras.

Gus-Brautbar Y, Johnson D, Zhang L, Sun H, Wang P, Zhang S, Zhang L, Chen YH.

Mol Cell. 2012 Mar 9;45(5):610-8. doi: 10.1016/j.molcel.2012.01.006. Epub 2012 Feb 8.

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