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Results: 1 to 20 of 40


Disulfide cross-linked micelles of novel HDAC inhibitor thailandepsin A for the treatment of breast cancer.

Xiao K, Li YP, Wang C, Ahmad S, Vu M, Kuma K, Cheng YQ, Lam KS.

Biomaterials. 2015 Jul 17;67:183-193. doi: 10.1016/j.biomaterials.2015.07.033. [Epub ahead of print]


Determination of thailandepsin B in rat plasma with a LC-MS/MS method.

Cheng Z, Ding L, Zhang Y, Chen G, Chen C, Cheng YQ, Jiang H.

Bioanalysis. 2015;7(1):39-52. doi: 10.4155/bio.14.264.


Identification and characterization of the spiruchostatin biosynthetic gene cluster enable yield improvement by overexpressing a transcriptional activator.

Potharla VY, Wang C, Cheng YQ.

J Ind Microbiol Biotechnol. 2014 Sep;41(9):1457-65. doi: 10.1007/s10295-014-1474-8. Epub 2014 Jun 29.


The novel histone deacetylase inhibitor thailandepsin A inhibits anaplastic thyroid cancer growth.

Weinlander E, Somnay Y, Harrison AD, Wang C, Cheng YQ, Jaskula-Sztul R, Yu XM, Chen H.

J Surg Res. 2014 Jul;190(1):191-7. doi: 10.1016/j.jss.2014.02.042. Epub 2014 Feb 28.


The structural basis of an NADPÔü║-independent dithiol oxidase in FK228 biosynthesis.

Li J, Wang C, Zhang ZM, Cheng YQ, Zhou J.

Sci Rep. 2014 Feb 20;4:4145. doi: 10.1038/srep04145.


Genome-guided discovery of diverse natural products from Burkholderia sp.

Liu X, Cheng YQ.

J Ind Microbiol Biotechnol. 2014 Feb;41(2):275-84. doi: 10.1007/s10295-013-1376-1. Epub 2013 Nov 9. Review.


Activation of ClpP protease by ADEP antibiotics: insights from hydrogen exchange mass spectrometry.

Sowole MA, Alexopoulos JA, Cheng YQ, Ortega J, Konermann L.

J Mol Biol. 2013 Nov 15;425(22):4508-19. doi: 10.1016/j.jmb.2013.08.005. Epub 2013 Aug 13.


Structural determinants stabilizing the axial channel of ClpP for substrate translocation.

Alexopoulos J, Ahsan B, Homchaudhuri L, Husain N, Cheng YQ, Ortega J.

Mol Microbiol. 2013 Oct;90(1):167-80. doi: 10.1111/mmi.12356. Epub 2013 Aug 23.


Inactivation of cyclic Di-GMP binding protein TDE0214 affects the motility, biofilm formation, and virulence of Treponema denticola.

Bian J, Liu X, Cheng YQ, Li C.

J Bacteriol. 2013 Sep;195(17):3897-905. doi: 10.1128/JB.00610-13. Epub 2013 Jun 21.


Isolation and characterization of spliceostatin B, a new analogue of FR901464, from Pseudomonas sp. No. 2663.

Liu X, Biswas S, Tang GL, Cheng YQ.

J Antibiot (Tokyo). 2013 Sep;66(9):555-8. doi: 10.1038/ja.2013.38. Epub 2013 May 8. No abstract available.


Effects of thailanstatins on glucocorticoid response in trabecular meshwork and steroid-induced glaucoma.

Jain A, Liu X, Wordinger RJ, Yorio T, Cheng YQ, Clark AF.

Invest Ophthalmol Vis Sci. 2013 May 3;54(5):3137-42. doi: 10.1167/iovs.12-11480.


Genomics-guided discovery of thailanstatins A, B, and C As pre-mRNA splicing inhibitors and antiproliferative agents from Burkholderia thailandensis MSMB43.

Liu X, Biswas S, Berg MG, Antapli CM, Xie F, Wang Q, Tang MC, Tang GL, Zhang L, Dreyfuss G, Cheng YQ.

J Nat Prod. 2013 Apr 26;76(4):685-93. doi: 10.1021/np300913h. Epub 2013 Mar 21.


Cyclo-(-l-prolyl-l-valinyl-) from Burkholderia thailandensis MSMB43.

Liu XY, Wang C, Cheng YQ.

Acta Crystallogr Sect E Struct Rep Online. 2012 Nov 1;68(Pt 11):o3182-3. doi: 10.1107/S1600536812043000. Epub 2012 Oct 20.


FK228 from Burkholderia thailandensis MSMB43.

Liu XY, Wang C, Cheng YQ.

Acta Crystallogr Sect E Struct Rep Online. 2012 Sep 1;68(Pt 9):o2757-8. doi: 10.1107/S160053681203601X. Epub 2012 Aug 23.


Revised genome sequence of Burkholderia thailandensis MSMB43 with improved annotation.

Zhuo Y, Liu L, Wang Q, Liu X, Ren B, Liu M, Ni P, Cheng YQ, Zhang L.

J Bacteriol. 2012 Sep;194(17):4749-50. doi: 10.1128/JB.00931-12.


Extractive fermentation for enhanced production of thailandepsin A from Burkholderia thailandensis E264 using polyaromatic adsorbent resin Diaion HP-20.

Liu B, Hui J, Cheng YQ, Zhang X.

J Ind Microbiol Biotechnol. 2012 May;39(5):767-76. doi: 10.1007/s10295-011-1073-x. Epub 2012 Jan 14.


Thailandepsin a.

Wang C, Cheng YQ.

Acta Crystallogr Sect E Struct Rep Online. 2011 Nov;67(Pt 11):o2948-9. doi: 10.1107/S1600536811041390. Epub 2011 Oct 12.


Activators of cylindrical proteases as antimicrobials: identification and development of small molecule activators of ClpP protease.

Leung E, Datti A, Cossette M, Goodreid J, McCaw SE, Mah M, Nakhamchik A, Ogata K, El Bakkouri M, Cheng YQ, Wodak SJ, Eger BT, Pai EF, Liu J, Gray-Owen S, Batey RA, Houry WA.

Chem Biol. 2011 Sep 23;18(9):1167-78. doi: 10.1016/j.chembiol.2011.07.023.

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