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Results: 1 to 20 of 25

1.

Intrinsic subtypes of high-grade bladder cancer reflect the hallmarks of breast cancer biology.

Damrauer JS, Hoadley KA, Chism DD, Fan C, Tiganelli CJ, Wobker SE, Yeh JJ, Milowsky MI, Iyer G, Parker JS, Kim WY.

Proc Natl Acad Sci U S A. 2014 Feb 25;111(8):3110-5. doi: 10.1073/pnas.1318376111. Epub 2014 Feb 11.

PMID:
24520177
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Erythropoietin promotes breast tumorigenesis through tumor-initiating cell self-renewal.

Zhou B, Damrauer JS, Bailey ST, Hadzic T, Jeong Y, Clark K, Fan C, Murphy L, Lee CY, Troester MA, Miller CR, Jin J, Darr D, Perou CM, Levine RL, Diehn M, Kim WY.

J Clin Invest. 2014 Feb 3;124(2):553-63. doi: 10.1172/JCI69804. Epub 2014 Jan 2.

PMID:
24435044
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Codelivery of VEGF siRNA and gemcitabine monophosphate in a single nanoparticle formulation for effective treatment of NSCLC.

Zhang Y, Schwerbrock NM, Rogers AB, Kim WY, Huang L.

Mol Ther. 2013 Aug;21(8):1559-69. doi: 10.1038/mt.2013.120. Epub 2013 Jun 18.

PMID:
23774791
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Metabolic and functional genomic studies identify deoxythymidylate kinase as a target in LKB1-mutant lung cancer.

Liu Y, Marks K, Cowley GS, Carretero J, Liu Q, Nieland TJ, Xu C, Cohoon TJ, Gao P, Zhang Y, Chen Z, Altabef AB, Tchaicha JH, Wang X, Choe S, Driggers EM, Zhang J, Bailey ST, Sharpless NE, Hayes DN, Patel NM, Janne PA, Bardeesy N, Engelman JA, Manning BD, Shaw RJ, Asara JM, Scully R, Kimmelman A, Byers LA, Gibbons DL, Wistuba II, Heymach JV, Kwiatkowski DJ, Kim WY, Kung AL, Gray NS, Root DE, Cantley LC, Wong KK.

Cancer Discov. 2013 Aug;3(8):870-9. doi: 10.1158/2159-8290.CD-13-0015. Epub 2013 May 28.

PMID:
23715154
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Stearoyl co-A desaturase 1 as a ccRCC therapeutic target: death by stress.

Leung JY, Kim WY.

Clin Cancer Res. 2013 Jun 15;19(12):3111-3. doi: 10.1158/1078-0432.CCR-13-0800. Epub 2013 May 24.

PMID:
23709675
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

HIF1α and HIF2α independently activate SRC to promote melanoma metastases.

Hanna SC, Krishnan B, Bailey ST, Moschos SJ, Kuan PF, Shimamura T, Osborne LD, Siegel MB, Duncan LM, O'Brien ET 3rd, Superfine R, Miller CR, Simon MC, Wong KK, Kim WY.

J Clin Invest. 2013 May 1;123(5):2078-93. doi: 10.1172/JCI66715. Epub 2013 Apr 8.

PMID:
23563312
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Systemic delivery of gemcitabine triphosphate via LCP nanoparticles for NSCLC and pancreatic cancer therapy.

Zhang Y, Kim WY, Huang L.

Biomaterials. 2013 Apr;34(13):3447-58. doi: 10.1016/j.biomaterials.2013.01.063. Epub 2013 Feb 4.

PMID:
23380359
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Regulation of hypoxia-inducible factor 2-a is essential for integrity of the glomerular barrier.

Ding M, Coward RJ, Jeansson M, Kim W, Quaggin SE.

Am J Physiol Renal Physiol. 2013 Jan 1;304(1):F120-6. doi: 10.1152/ajprenal.00416.2012. Epub 2012 Oct 10.

PMID:
23054256
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

State of the science: an update on renal cell carcinoma.

Jonasch E, Futreal PA, Davis IJ, Bailey ST, Kim WY, Brugarolas J, Giaccia AJ, Kurban G, Pause A, Frydman J, Zurita AJ, Rini BI, Sharma P, Atkins MB, Walker CL, Rathmell WK.

Mol Cancer Res. 2012 Jul;10(7):859-80. doi: 10.1158/1541-7786.MCR-12-0117. Epub 2012 May 25. Review.

PMID:
22638109
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Dynamic reprogramming of the kinome in response to targeted MEK inhibition in triple-negative breast cancer.

Duncan JS, Whittle MC, Nakamura K, Abell AN, Midland AA, Zawistowski JS, Johnson NL, Granger DA, Jordan NV, Darr DB, Usary J, Kuan PF, Smalley DM, Major B, He X, Hoadley KA, Zhou B, Sharpless NE, Perou CM, Kim WY, Gomez SM, Chen X, Jin J, Frye SV, Earp HS, Graves LM, Johnson GL.

Cell. 2012 Apr 13;149(2):307-21. doi: 10.1016/j.cell.2012.02.053.

PMID:
22500798
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Double-blind, randomized trial of docetaxel plus vandetanib versus docetaxel plus placebo in platinum-pretreated metastatic urothelial cancer.

Choueiri TK, Ross RW, Jacobus S, Vaishampayan U, Yu EY, Quinn DI, Hahn NM, Hutson TE, Sonpavde G, Morrissey SC, Buckle GC, Kim WY, Petrylak DP, Ryan CW, Eisenberger MA, Mortazavi A, Bubley GJ, Taplin ME, Rosenberg JE, Kantoff PW.

J Clin Oncol. 2012 Feb 10;30(5):507-12. doi: 10.1200/JCO.2011.37.7002. Epub 2011 Dec 19.

PMID:
22184381
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Drug efficacy testing in mice.

Kim WY, Sharpless NE.

Curr Top Microbiol Immunol. 2012;355:19-38. doi: 10.1007/82_2011_160.

PMID:
21823029
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Loss of JAK2 regulation via a heterodimeric VHL-SOCS1 E3 ubiquitin ligase underlies Chuvash polycythemia.

Russell RC, Sufan RI, Zhou B, Heir P, Bunda S, Sybingco SS, Greer SN, Roche O, Heathcote SA, Chow VW, Boba LM, Richmond TD, Hickey MM, Barber DL, Cheresh DA, Simon MC, Irwin MS, Kim WY, Ohh M.

Nat Med. 2011 Jun 19;17(7):845-53. doi: 10.1038/nm.2370.

PMID:
21685897
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Two sides to every story: the HIF-dependent and HIF-independent functions of pVHL.

Li M, Kim WY.

J Cell Mol Med. 2011 Feb;15(2):187-95. doi: 10.1111/j.1582-4934.2010.01238.x. Review.

PMID:
21155973
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

HIF, hypoxia and the role of angiogenesis in non-small cell lung cancer.

Jackson AL, Zhou B, Kim WY.

Expert Opin Ther Targets. 2010 Oct;14(10):1047-57. doi: 10.1517/14728222.2010.511617. Review.

PMID:
20854179
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

A phase I trial of sorafenib combined with cisplatin/etoposide or carboplatin/pemetrexed in refractory solid tumor patients.

Davies JM, Dhruva NS, Walko CM, Socinski MA, Bernard S, Hayes DN, Kim WY, Ivanova A, Keller K, Hilbun LR, Chiu M, Dees EC, Stinchcombe TE.

Lung Cancer. 2011 Feb;71(2):151-5. doi: 10.1016/j.lungcan.2010.05.022. Epub 2010 Jul 1.

PMID:
20580118
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Integrative genomic and proteomic analyses identify targets for Lkb1-deficient metastatic lung tumors.

Carretero J, Shimamura T, Rikova K, Jackson AL, Wilkerson MD, Borgman CL, Buttarazzi MS, Sanofsky BA, McNamara KL, Brandstetter KA, Walton ZE, Gu TL, Silva JC, Crosby K, Shapiro GI, Maira SM, Ji H, Castrillon DH, Kim CF, García-Echeverría C, Bardeesy N, Sharpless NE, Hayes ND, Kim WY, Engelman JA, Wong KK.

Cancer Cell. 2010 Jun 15;17(6):547-59. doi: 10.1016/j.ccr.2010.04.026.

PMID:
20541700
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

HIF2alpha cooperates with RAS to promote lung tumorigenesis in mice.

Kim WY, Perera S, Zhou B, Carretero J, Yeh JJ, Heathcote SA, Jackson AL, Nikolinakos P, Ospina B, Naumov G, Brandstetter KA, Weigman VJ, Zaghlul S, Hayes DN, Padera RF, Heymach JV, Kung AL, Sharpless NE, Kaelin WG Jr, Wong KK.

J Clin Invest. 2009 Aug;119(8):2160-70.

PMID:
19662677
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

CD200 is induced by ERK and is a potential therapeutic target in melanoma.

Petermann KB, Rozenberg GI, Zedek D, Groben P, McKinnon K, Buehler C, Kim WY, Shields JM, Penland S, Bear JE, Thomas NE, Serody JS, Sharpless NE.

J Clin Invest. 2007 Dec;117(12):3922-9.

PMID:
18008004
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

pVHL acts as an adaptor to promote the inhibitory phosphorylation of the NF-kappaB agonist Card9 by CK2.

Yang H, Minamishima YA, Yan Q, Schlisio S, Ebert BL, Zhang X, Zhang L, Kim WY, Olumi AF, Kaelin WG Jr.

Mol Cell. 2007 Oct 12;28(1):15-27.

PMID:
17936701
[PubMed - indexed for MEDLINE]
Free PMC Article

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