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Results: 15

1.

Overexpression of the steroidogenic enzyme cytochrome P450 side chain cleavage in the ventral tegmental area increases 3α,5α-THP and reduces long-term operant ethanol self-administration.

Cook JB, Werner DF, Maldonado-Devincci AM, Leonard MN, Fisher KR, O'Buckley TK, Porcu P, McCown TJ, Besheer J, Hodge CW, Morrow AL.

J Neurosci. 2014 Apr 23;34(17):5824-34. doi: 10.1523/JNEUROSCI.4733-13.2014.

2.

The cytokine mRNA increase induced by withdrawal from chronic ethanol in the sterile environment of brain is mediated by CRF and HMGB1 release.

Whitman BA, Knapp DJ, Werner DF, Crews FT, Breese GR.

Alcohol Clin Exp Res. 2013 Dec;37(12):2086-97. doi: 10.1111/acer.12189. Epub 2013 Jul 29.

3.

Ethanol activation of protein kinase A regulates GABAA α1 receptor function and trafficking in cultured cerebral cortical neurons.

Carlson SL, Kumar S, Werner DF, Comerford CE, Morrow AL.

J Pharmacol Exp Ther. 2013 May;345(2):317-25. doi: 10.1124/jpet.112.201954. Epub 2013 Feb 13.

4.

Ethanol Activation of Protein Kinase A Regulates GABA(A) Receptor Subunit Expression in the Cerebral Cortex and Contributes to Ethanol-Induced Hypnosis.

Kumar S, Ren Q, Beckley JH, O'Buckley TK, Gigante ED, Santerre JL, Werner DF, Morrow AL.

Front Neurosci. 2012 Apr 9;6:44. doi: 10.3389/fnins.2012.00044. eCollection 2012.

5.

PKCγ is required for ethanol-induced increases in GABA(A) receptor α4 subunit expression in cultured cerebral cortical neurons.

Werner DF, Kumar S, Criswell HE, Suryanarayanan A, Fetzer JA, Comerford CE, Morrow AL.

J Neurochem. 2011 Feb;116(4):554-63. doi: 10.1111/j.1471-4159.2010.07140.x. Epub 2011 Jan 19.

6.

Loss of ethanol conditioned taste aversion and motor stimulation in knockin mice with ethanol-insensitive α2-containing GABA(A) receptors.

Blednov YA, Borghese CM, McCracken ML, Benavidez JM, Geil CR, Osterndorff-Kahanek E, Werner DF, Iyer S, Swihart A, Harrison NL, Homanics GE, Harris RA.

J Pharmacol Exp Ther. 2011 Jan;336(1):145-54. doi: 10.1124/jpet.110.171645. Epub 2010 Sep 27.

7.

Inhaled anesthetic responses of recombinant receptors and knockin mice harboring α2(S270H/L277A) GABA(A) receptor subunits that are resistant to isoflurane.

Werner DF, Swihart A, Rau V, Jia F, Borghese CM, McCracken ML, Iyer S, Fanselow MS, Oh I, Sonner JM, Eger EI 2nd, Harrison NL, Harris RA, Homanics GE.

J Pharmacol Exp Ther. 2011 Jan;336(1):134-44. doi: 10.1124/jpet.110.170431. Epub 2010 Aug 31.

8.

The role of GABA(A) receptors in the acute and chronic effects of ethanol: a decade of progress.

Kumar S, Porcu P, Werner DF, Matthews DB, Diaz-Granados JL, Helfand RS, Morrow AL.

Psychopharmacology (Berl). 2009 Sep;205(4):529-64. doi: 10.1007/s00213-009-1562-z. Epub 2009 May 20. Review.

9.

Alcohol-induced tolerance and physical dependence in mice with ethanol insensitive alpha1 GABA A receptors.

Werner DF, Swihart AR, Ferguson C, Lariviere WR, Harrison NL, Homanics GE.

Alcohol Clin Exp Res. 2009 Feb;33(2):289-99. doi: 10.1111/j.1530-0277.2008.00832.x. Epub 2008 Nov 19.

10.

Isoflurane modulates excitability in the mouse thalamus via GABA-dependent and GABA-independent mechanisms.

Ying SW, Werner DF, Homanics GE, Harrison NL, Goldstein PA.

Neuropharmacology. 2009 Feb;56(2):438-47. doi: 10.1016/j.neuropharm.2008.09.015. Epub 2008 Oct 9.

11.

Mice with targeted genetic reduction of GABA(A) receptor alpha1 subunits display performance differences in Morris water maze tasks.

Berry RB, Werner DF, Wang X, Jablonski MM, Homanics GE, Mittleman G, Matthews DB.

Neurobiol Learn Mem. 2008 Oct;90(3):580-3. doi: 10.1016/j.nlm.2008.06.004. Epub 2008 Jul 26.

12.

Normal acute behavioral responses to moderate/high dose ethanol in GABAA receptor alpha 4 subunit knockout mice.

Chandra D, Werner DF, Liang J, Suryanarayanan A, Harrison NL, Spigelman I, Olsen RW, Homanics GE.

Alcohol Clin Exp Res. 2008 Jan;32(1):10-8. Epub 2007 Dec 12.

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GABAA receptor alpha 4 subunits mediate extrasynaptic inhibition in thalamus and dentate gyrus and the action of gaboxadol.

Chandra D, Jia F, Liang J, Peng Z, Suryanarayanan A, Werner DF, Spigelman I, Houser CR, Olsen RW, Harrison NL, Homanics GE.

Proc Natl Acad Sci U S A. 2006 Oct 10;103(41):15230-5. Epub 2006 Sep 27.

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