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Year Number of Results
1976 1
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1987 2
1988 2
1989 10
1990 7
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1993 12
1994 18
1995 11
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1999 15
2000 16
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2002 34
2003 26
2004 37
2005 53
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2007 65
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2009 95
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2022 180
2023 199
2024 97

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Page 1
Advances of Vibrational Circular Dichroism (VCD) in bioanalytical chemistry. A review.
Kurouski D. Kurouski D. Anal Chim Acta. 2017 Oct 16;990:54-66. doi: 10.1016/j.aca.2017.08.014. Epub 2017 Aug 18. Anal Chim Acta. 2017. PMID: 29029743 Free PMC article. Review.
VCD can be also used to determine structure of large macromolecules. This review highlights the most recent advances of VCD in bioanalytical chemistry. It shows that VCD is capable of unraveling supramolecular organization of peptides, proteins, saccharides, …
VCD can be also used to determine structure of large macromolecules. This review highlights the most recent advances of VCD in …
VCD-induced menopause mouse model reveals reprogramming of hepatic metabolism.
Kumari R, Ponte ME, Franczak E, Prom JC, O'Neil MF, Sardiu ME, Lutkewitte AJ, Shankar K, Morris EM, Thyfault JP. Kumari R, et al. bioRxiv [Preprint]. 2023 Dec 14:2023.12.14.571644. doi: 10.1101/2023.12.14.571644. bioRxiv. 2023. PMID: 38168213 Free PMC article. Updated. Preprint.
However, the transition to a HFHS lowered cage activity in VCD mice. A chronic HFHS diet (16 weeks) significantly increased weight gain, fat mass, and hepatic steatosis in VCD-treated mice compared to HFHS-fed controls. ...Also, liver RNA sequencing revealed that …
However, the transition to a HFHS lowered cage activity in VCD mice. A chronic HFHS diet (16 weeks) significantly increased weight ga …
VCD studies on chiral characters of metal complex oligomers.
Sato H, Yamagishi A. Sato H, et al. Int J Mol Sci. 2013 Jan 7;14(1):964-78. doi: 10.3390/ijms14010964. Int J Mol Sci. 2013. PMID: 23296273 Free PMC article. Review.
The present article reviews the results on the application of vibrational circular dichroism (VCD) spectroscopy to the study of stereochemical properties of chiral metal complexes in solution. ...The investigation is further extended to the oligomers of beta-diketonato com …
The present article reviews the results on the application of vibrational circular dichroism (VCD) spectroscopy to the study of stere …
Modelling solute-solvent interactions in VCD spectra analysis with the micro-solvation approach.
Merten C. Merten C. Phys Chem Chem Phys. 2023 Nov 8;25(43):29404-29414. doi: 10.1039/d3cp03408a. Phys Chem Chem Phys. 2023. PMID: 37881890 Review.
Vibrational circular dichroism (VCD) spectroscopy has become an important part of the (stereo-)chemists' toolbox as a reliable method for the determination of absolute configurations. ...We thus also discuss its limitations and outline the next steps that method developmen …
Vibrational circular dichroism (VCD) spectroscopy has become an important part of the (stereo-)chemists' toolbox as a reliable method …
VCD spectroscopy reveals conformational changes of chiral crown ethers upon complexation of potassium and ammonium cations.
Weirich L, Tusha G, Engelage E, Schäfer LV, Merten C. Weirich L, et al. Phys Chem Chem Phys. 2022 May 18;24(19):11721-11728. doi: 10.1039/d2cp01309f. Phys Chem Chem Phys. 2022. PMID: 35506489
In addition, the asymmetric NH(3)-deformation modes are found to gain VCD intensity through an induced VCD process. An analysis of the vibrational spectra enables a differentiation of VCD active and inactive guest modes: There appears to be a correlation betw …
In addition, the asymmetric NH(3)-deformation modes are found to gain VCD intensity through an induced VCD process. An analysi …
VCD spectra of chiral naphthalene-1-carboxamides in the solid-state.
Rode JE, Łyczko K, Kaczorek D, Kawęcki R, Dobrowolski JC. Rode JE, et al. Spectrochim Acta A Mol Biomol Spectrosc. 2024 Apr 5;310:123939. doi: 10.1016/j.saa.2024.123939. Epub 2024 Jan 24. Spectrochim Acta A Mol Biomol Spectrosc. 2024. PMID: 38301569
For (i) Me, Ph and pClPh (R)-enantiomers, two (+)(-) bands were distinguished and for (ii) nBu and pMePh ones, one VCD band with right-side asymmetry was found. For (iii) oMeOPh the VCD pattern cannot be unambiguously assigned. Thus, the VCD spectra in the nu …
For (i) Me, Ph and pClPh (R)-enantiomers, two (+)(-) bands were distinguished and for (ii) nBu and pMePh ones, one VCD band with righ …
The determination of the absolute configurations of chiral molecules using vibrational circular dichroism (VCD) spectroscopy.
Stephens PJ, Devlin FJ, Pan JJ. Stephens PJ, et al. Chirality. 2008 May 15;20(5):643-63. doi: 10.1002/chir.20477. Chirality. 2008. PMID: 17955495 Review.
The vibrational circular dichroism (VCD) spectra of the two enantiomers of a chiral molecule are of equal magnitude and opposite sign: i.e. mirror-image enantiomers give mirror-image VCD spectra. In principle, the absolute configuration (AC) of a chiral molecule can …
The vibrational circular dichroism (VCD) spectra of the two enantiomers of a chiral molecule are of equal magnitude and opposite sign …
Impact of Induction With VCD Versus VRD on the Outcome of Patients With Multiple Myeloma After an Autologous Hematopoietic Stem Cell Transplantation.
Afrough A, Pasvolsky O, Ma J, Srour S, Bashir Q, Saini N, Hosing C, Popat UR, Kebriaei P, Delgado R, Ullah MR, Murphy R, Manasanch EE, Lee HC, Kaufman GP, Patel KK, Thomas SK, Weber DM, Orlowski RZ, Shpall EJ, Champlin RE, Qazilbash MH. Afrough A, et al. Transplant Cell Ther. 2022 Jun;28(6):307.e1-307.e8. doi: 10.1016/j.jtct.2022.03.020. Epub 2022 Mar 22. Transplant Cell Ther. 2022. PMID: 35331973 Free article.
However, previous studies comparing VCD and VRD showed disparate results. The goal of this retrospective study was to compare the "real-world" results of VCD and VRD in transplant-eligible MM patients outside of a clinical trial. ...There was no difference in the re …
However, previous studies comparing VCD and VRD showed disparate results. The goal of this retrospective study was to compare the "re …
Comorbid amyloid-beta pathology affects clinical and imaging features in VCD.
Leijenaar JF, Groot C, Sudre CH, Bergeron D, Leeuwis AE, Cardoso MJ, Carrasco FP, Laforce R Jr, Barkhof F, van der Flier WM, Scheltens P, Prins ND, Ossenkoppele R. Leijenaar JF, et al. Alzheimers Dement. 2020 Feb;16(2):354-364. doi: 10.1016/j.jalz.2019.08.190. Epub 2020 Jan 4. Alzheimers Dement. 2020. PMID: 31786129 Free article.
Patients were divided into Abeta+ mild-VCD (n = 84), Abeta- mild-VCD (n = 68), Abeta+ major-VCD (n = 31), and Abeta- major-VCD (n = 35). ...Atrophy patterns did not differ between Abeta+ and Abeta- VCD group. DISCUSSION: Comorbid Abeta pathology …
Patients were divided into Abeta+ mild-VCD (n = 84), Abeta- mild-VCD (n = 68), Abeta+ major-VCD (n = 31), and Abeta- ma …
Induced VCD and conformational chirality in host-guest complexes of a chiral ammonium salt with crown ethers.
Weirich L , Merten C . Weirich L , et al. Phys Chem Chem Phys. 2021 Sep 14;23(34):18300-18307. doi: 10.1039/d1cp01846a. Epub 2021 Jun 11. Phys Chem Chem Phys. 2021. PMID: 34114592
Based on a detailed conformational analysis, we investigate the origin of these signatures and discuss induced VCD (iVCD) and conformational chirality as possible sources of VCD intensity. ...The study thus demonstrates the suitability of VCD spectroscopy for …
Based on a detailed conformational analysis, we investigate the origin of these signatures and discuss induced VCD (iVCD) and conform …
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