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Results: 1 to 20 of 41

1.

Cell cycle population effects in perturbation studies.

O'Duibhir E, Lijnzaad P, Benschop JJ, Lenstra TL, van Leenen D, Groot Koerkamp MJ, Margaritis T, Brok MO, Kemmeren P, Holstege FC.

Mol Syst Biol. 2014 Jun 21;10(6):732. doi: 10.15252/msb.20145172.

PMID:
24952590
[PubMed - in process]
Free Article
2.

The two main forms of histiocytic sarcoma in the predisposed Flatcoated retriever dog display variation in gene expression.

Boerkamp KM, van Steenbeek FG, Penning LC, Groot Koerkamp MJ, van Leenen D, Vos-Loohuis M, Grinwis GC, Rutteman GR.

PLoS One. 2014 Jun 2;9(6):e98258. doi: 10.1371/journal.pone.0098258. eCollection 2014.

PMID:
24886914
[PubMed - in process]
Free PMC Article
3.

Large-scale genetic perturbations reveal regulatory networks and an abundance of gene-specific repressors.

Kemmeren P, Sameith K, van de Pasch LA, Benschop JJ, Lenstra TL, Margaritis T, O'Duibhir E, Apweiler E, van Wageningen S, Ko CW, van Heesch S, Kashani MM, Ampatziadis-Michailidis G, Brok MO, Brabers NA, Miles AJ, Bouwmeester D, van Hooff SR, van Bakel H, Sluiters E, Bakker LV, Snel B, Lijnzaad P, van Leenen D, Groot Koerkamp MJ, Holstege FC.

Cell. 2014 Apr 24;157(3):740-52. doi: 10.1016/j.cell.2014.02.054.

PMID:
24766815
[PubMed - indexed for MEDLINE]
4.

The role of Ctk1 kinase in termination of small non-coding RNAs.

Lenstra TL, Tudek A, Clauder S, Xu Z, Pachis ST, van Leenen D, Kemmeren P, Steinmetz LM, Libri D, Holstege FC.

PLoS One. 2013 Dec 4;8(12):e80495. doi: 10.1371/journal.pone.0080495. eCollection 2013.

PMID:
24324601
[PubMed - in process]
Free PMC Article
5.

Correction: Aberrant Gene Expression in Dogs with Portosystemic Shunts.

van Steenbeek FG, Van den Bossche L, Grinwis GC, Kummeling A, van Gils IH, Koerkamp MJ, van Leenen D, Holstege FC, Penning LC, Rothuizen J, Leegwater PA, Spee B.

PLoS One. 2013 Oct 15;8(10). doi: 10.1371/annotation/5cccaae3-f06c-413f-857e-46546e87fce1. eCollection 2013.

PMID:
24204461
[PubMed - as supplied by publisher]
Free PMC Article
6.

Early adipogenesis is regulated through USP7-mediated deubiquitination of the histone acetyltransferase TIP60.

Gao Y, Koppen A, Rakhshandehroo M, Tasdelen I, van de Graaf SF, van Loosdregt J, van Beekum O, Hamers N, van Leenen D, Berkers CR, Berger R, Holstege FC, Coffer PJ, Brenkman AB, Ovaa H, Kalkhoven E.

Nat Commun. 2013;4:2656. doi: 10.1038/ncomms3656.

PMID:
24141283
[PubMed - indexed for MEDLINE]
7.

Gene expression profiling of histiocytic sarcomas in a canine model: the predisposed flatcoated retriever dog.

Boerkamp KM, van der Kooij M, van Steenbeek FG, van Wolferen ME, Groot Koerkamp MJ, van Leenen D, Grinwis GC, Penning LC, Wiemer EA, Rutteman GR.

PLoS One. 2013 Aug 1;8(8):e71094. doi: 10.1371/journal.pone.0071094. Print 2013.

PMID:
23936488
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Centromere binding and a conserved role in chromosome stability for SUMO-dependent ubiquitin ligases.

van de Pasch LA, Miles AJ, Nijenhuis W, Brabers NA, van Leenen D, Lijnzaad P, Brown MK, Ouellet J, Barral Y, Kops GJ, Holstege FC.

PLoS One. 2013 Jun 13;8(6):e65628. doi: 10.1371/journal.pone.0065628. Print 2013.

PMID:
23785440
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Balancing of histone H3K4 methylation states by the Kdm5c/SMCX histone demethylase modulates promoter and enhancer function.

Outchkourov NS, Muiño JM, Kaufmann K, van Ijcken WF, Groot Koerkamp MJ, van Leenen D, de Graaf P, Holstege FC, Grosveld FG, Timmers HT.

Cell Rep. 2013 Apr 25;3(4):1071-9. doi: 10.1016/j.celrep.2013.02.030. Epub 2013 Mar 28.

PMID:
23545502
[PubMed - indexed for MEDLINE]
Free Article
10.

Altered subcellular localization of heat shock protein 90 is associated with impaired expression of the aryl hydrocarbon receptor pathway in dogs.

van Steenbeek FG, Spee B, Penning LC, Kummeling A, van Gils IH, Grinwis GC, Van Leenen D, Holstege FC, Vos-Loohuis M, Rothuizen J, Leegwater PA.

PLoS One. 2013;8(3):e57973. doi: 10.1371/journal.pone.0057973. Epub 2013 Mar 5.

PMID:
23472125
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Aberrant gene expression in dogs with portosystemic shunts.

van Steenbeek FG, Van den Bossche L, Grinwis GC, Kummeling A, van Gils IH, Koerkamp MJ, van Leenen D, Holstege FC, Penning LC, Rothuizen J, Leegwater PA, Spee B.

PLoS One. 2013;8(2):e57662. doi: 10.1371/journal.pone.0057662. Epub 2013 Feb 25.

PMID:
23451256
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Gene expression profiling of early intervertebral disc degeneration reveals a down-regulation of canonical Wnt signaling and caveolin-1 expression: implications for development of regenerative strategies.

Smolders LA, Meij BP, Onis D, Riemers FM, Bergknut N, Wubbolts R, Grinwis GC, Houweling M, Groot Koerkamp MJ, van Leenen D, Holstege FC, Hazewinkel HA, Creemers LB, Penning LC, Tryfonidou MA.

Arthritis Res Ther. 2013 Jan 29;15(1):R23. [Epub ahead of print]

PMID:
23360510
[PubMed - as supplied by publisher]
Free PMC Article
13.

Exploring gene expression signatures for predicting disease free survival after resection of colorectal cancer liver metastases.

Snoeren N, van Hooff SR, Adam R, van Hillegersberg R, Voest EE, Guettier C, van Diest PJ, Nijkamp MW, Brok MO, van Leenen D, Koerkamp MJ, Holstege FC, Rinkes IH.

PLoS One. 2012;7(11):e49442. doi: 10.1371/journal.pone.0049442. Epub 2012 Nov 21.

PMID:
23185333
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Two distinct repressive mechanisms for histone 3 lysine 4 methylation through promoting 3'-end antisense transcription.

Margaritis T, Oreal V, Brabers N, Maestroni L, Vitaliano-Prunier A, Benschop JJ, van Hooff S, van Leenen D, Dargemont C, Géli V, Holstege FC.

PLoS Genet. 2012 Sep;8(9):e1002952. doi: 10.1371/journal.pgen.1002952. Epub 2012 Sep 20.

PMID:
23028359
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Yeast glucose pathways converge on the transcriptional regulation of trehalose biosynthesis.

Apweiler E, Sameith K, Margaritis T, Brabers N, van de Pasch L, Bakker LV, van Leenen D, Holstege FC, Kemmeren P.

BMC Genomics. 2012 Jun 14;13:239. doi: 10.1186/1471-2164-13-239.

PMID:
22697265
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Retinoic acid-dependent and -independent gene-regulatory pathways of Pitx3 in meso-diencephalic dopaminergic neurons.

Jacobs FM, Veenvliet JV, Almirza WH, Hoekstra EJ, von Oerthel L, van der Linden AJ, Neijts R, Koerkamp MG, van Leenen D, Holstege FC, Burbach JP, Smidt MP.

Development. 2011 Dec;138(23):5213-22. doi: 10.1242/dev.071704.

PMID:
22069189
[PubMed - indexed for MEDLINE]
Free Article
17.

The specificity and topology of chromatin interaction pathways in yeast.

Lenstra TL, Benschop JJ, Kim T, Schulze JM, Brabers NA, Margaritis T, van de Pasch LA, van Heesch SA, Brok MO, Groot Koerkamp MJ, Ko CW, van Leenen D, Sameith K, van Hooff SR, Lijnzaad P, Kemmeren P, Hentrich T, Kobor MS, Buratowski S, Holstege FC.

Mol Cell. 2011 May 20;42(4):536-49. doi: 10.1016/j.molcel.2011.03.026.

PMID:
21596317
[PubMed - indexed for MEDLINE]
Free Article
18.

Functional overlap and regulatory links shape genetic interactions between signaling pathways.

van Wageningen S, Kemmeren P, Lijnzaad P, Margaritis T, Benschop JJ, de Castro IJ, van Leenen D, Groot Koerkamp MJ, Ko CW, Miles AJ, Brabers N, Brok MO, Lenstra TL, Fiedler D, Fokkens L, Aldecoa R, Apweiler E, Taliadouros V, Sameith K, van de Pasch LA, van Hooff SR, Bakker LV, Krogan NJ, Snel B, Holstege FC.

Cell. 2010 Dec 10;143(6):991-1004. doi: 10.1016/j.cell.2010.11.021.

PMID:
21145464
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

A consensus of core protein complex compositions for Saccharomyces cerevisiae.

Benschop JJ, Brabers N, van Leenen D, Bakker LV, van Deutekom HW, van Berkum NL, Apweiler E, Lijnzaad P, Holstege FC, Kemmeren P.

Mol Cell. 2010 Jun 25;38(6):916-28. doi: 10.1016/j.molcel.2010.06.002.

PMID:
20620961
[PubMed - indexed for MEDLINE]
Free Article
20.

Early host responses to avian influenza A virus are prolonged and enhanced at transcriptional level depending on maturation of the immune system.

Reemers SS, van Leenen D, Koerkamp MJ, van Haarlem D, van de Haar P, van Eden W, Vervelde L.

Mol Immunol. 2010 May;47(9):1675-85. doi: 10.1016/j.molimm.2010.03.008. Epub 2010 Apr 10.

PMID:
20382427
[PubMed - indexed for MEDLINE]

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